L-Tryptophan ethyl ester hydrochloride

Base Information

• Chemical Name: L-Tryptophan ethyl ester hydrochloride
• CAS No.: 2899-28-7
• Molecular Formula: C₁₃H₁₆N₂O₂*ClH
• Molecular Weight: 268.743
• Hs Code.: 29339900
• European Community (EC) Number: 220-786-0
• ChEMBL ID: CHEMBL1222401
• Mol file: 2899-28-7.mol

Synonyms:2899-28-7;L-Tryptophan ethyl ester hydrochloride;ethyl l-tryptophanate hydrochloride;H-Trp-OEt.HCl;Ethyl L-tryptophanate HCl;L-Tryptophan ethyl ester, HCl;(S)-Tryptophan ethyl ester hydrochloride;EINECS 220-786-0;Ethyl L-tryptophanate monohydrochloride;NSC 401579;Tryptophan ethyl ester hydrochloride, L-;H-TRP-OET HCL;L-Tryptophan, ethyl ester, monohydrochloride;ethyl (2S)-2-amino-3-(1H-indol-3-yl)propanoate;hydrochloride;MFCD00038993;EthylL-tryptophanatehydrochloride;H-Trp-OEt. HCl;L-Trp-OEt⋅HCl;ethyl (2S)-2-amino-3-(1H-indol-3-yl)propanoate hydrochloride;TRYPTOPHAN-OET HCL;L-tryptophan ethyl ester HCl;C13H16N2O2.ClH;SCHEMBL133957;CHEMBL1222401;AKOS015898375;AKOS015924164;AM82285;s11605;L-Tryptophan, ethyl ester, hydrochloride;AS-80796;TS-00882;CS-0041281;T2981;(S)-Tryptophan ethyl ester hydrochloride, 97%;Tryptophan, ethyl ester, monohydrochloride, L-;L-Tryptophan, ethyl ester, hydrochloride (1:1);A847885;J-300271;Q-101611;L-Tryptophan ethyl ester hydrochloride, >=99.0% (AT);L-A-Amino-3-indolepropionic acid ethyl ester hydrochloride;(S)-ethyl 2-amino-3-(1H-indol-3-yl)propanoate hydrochloride;(S)-2-Amino-3-(3-indolyl)propionic Acid Ethyl Ester Hydrochloride

Chemical Property of L-Tryptophan ethyl ester hydrochloride

Chemical Property:

• Appearance/Colour: Light grey crystalline powder
• Vapor Pressure: 1.2E-06mmHg at 25°C
• Melting Point: 220-225 °C (dec.)
• Boiling Point: 401.2 °C at 760 mmHg
• PKA: pKa 7.10±0.05(H2O t=25.0±0.1 I=0.1(NaCl) N2atmosphere) (Uncertain);10.79±0.02 (H2O t=25.0±0.1 I=0.1(NaCl) N2atmosphere) (Uncertain)
• Flash Point: 196.4 °C
• PSA: 68.11000
• LogP: 3.10310
• Storage Temp.: 0-6°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 268.0978555
• Heavy Atom Count: 18
• Complexity: 270

Purity/Quality:

99% ^*data from raw suppliers

L-Tryptophan Ethyl Ester Hydrochloride >95.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC(=O)C(CC1=CNC2=CC=CC=C21)N.Cl
• Isomeric SMILES: CCOC(=O)[C@H](CC1=CNC2=CC=CC=C21)N.Cl

Technology Process of L-Tryptophan ethyl ester hydrochloride

There total 3 articles about L-Tryptophan ethyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.9%

ethanol (64-17-5) + L-Tryptophan (73-22-3,27732-43-0,80206-30-0,27813-82-7) → L-tryptophan ethyl ester hydrochloride (2899-28-7,6519-67-1,61535-49-7,67557-18-0,68401-14-9)

Guidance literature:

With hydrogenchloride; Reflux;

DOI:10.1021/jo8028168

Reference yield:

L-Tryptophan (73-22-3,27732-43-0,80206-30-0,27813-82-7) → L-tryptophan ethyl ester hydrochloride (2899-28-7,6519-67-1,61535-49-7,67557-18-0,68401-14-9)

Guidance literature:

With hydrogenchloride; In ethanol;

Reference yield:

→ L-tryptophan ethyl ester hydrochloride (2899-28-7,6519-67-1,61535-49-7,67557-18-0,68401-14-9)

Guidance literature:

upstream raw materials:

L-Tryptophan

ethanol

Downstream raw materials:

C₂₉H₄₆N₂O₃

C₂₈H₂₇N₃O₄

L-tryptophan ethyl ester

N-acetyl-L-tryptophane ethyl ester

Refernces

• 1、 -. "Preparation method of tryptophan ester hydrochloride". Paragraph 0045-0048. . Retrieved 2019/12/02.
• 2、 Fawzy,Abdallah,Zaafarany,Ahmed,Althagafi. "Thermodynamic, kinetic and mechanistic approach to the corrosion inhibition of carbon steel by new synthesized amino acids-based surfactants as green inhibitors in neutral and alkaline aqueous media". . p. 276 - 291. Retrieved 2018/06/13.