N,N-Dms

Base Information

• Chemical Name: N,N-Dms
• CAS No.: 119567-63-4
• Molecular Formula: C20H41NO2
• Molecular Weight: 327.31
• UNII: L9QRA71834
• DSSTox Substance ID: DTXSID801030509,DTXSID301189579
• Nikkaji Number: J3.073.985J
• Wikipedia: N,N-Dimethylsphingosine
• Wikidata: Q6477036
• Mol file: 119567-63-4.mol

Synonyms:(2R,3S,E)-2-(dimethylamino)octadec-4-ene-1,3-diol;D-erythro-N,N-dimethylsphingosine;DMS cpd;N,N-dimethyl-D-erythro-sphingosine;N,N-dimethyl-erythro-sphingosine;N,N-dimethylsphingosine;N,N-DMS

Chemical Property of N,N-Dms

Chemical Property:

• Appearance/Colour: Colourless to light yellow oil
• Vapor Pressure: 7.07E-10mmHg at 25°C
• Refractive Index: 1.483
• Boiling Point: 447.207 °C at 760 mmHg
• PKA: 13.72±0.20(Predicted)
• Flash Point: 186.073 °C
• PSA: 43.70000
• Density: 0.922 g/cm³
• LogP: 4.52710
• Storage Temp.: −20°C
• Solubility.: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
• XLogP3: 6.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 16
• Exact Mass: 327.313729551
• Heavy Atom Count: 23
• Complexity: 266

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N-Dimethylsphingosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F
• Statements: 11
• Safety Statements: 7-16

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCC=CC(C(CO)N(C)C)O
• Isomeric SMILES: CCCCCCCCCCCCC/C=C/[C@@H]([C@@H](CO)N(C)C)O
• Description: N,N-Dimethylsphingosine (119567-63-4) is a synthetic derivative of D-erythro-sphingosine (Cat.# 10-2287). Endogenous sphingolipid.1?Inhibits sphingosine kinase (IC50 = 5 μM).2?N,N-Dimethylsphingosine induces apoptosis in a variety of cell lines.3
• Uses: D-erythro-N,N-Dimethylsphingosine is general modulator of protein kinases . D-erythro-N,N-Dimethylsphingosine is implicated in neuropathic pain. N,N-Dimethylsphingosine is an inhibitor of sphingosine kinase (SPHK). It is a natural metabolite of sphingosine in some cancer cell lines and tissues. N,N-Dimethylsphingosine inhibited U937 cell SPHK with a Ki value of 3.1 μM. N,N-Dimethylsphingosine induces apoptosis, but it is not an inhibitor of protein kinase C. A general modulator of protein kinases.