n-Benzylidene-4-biphenylamine

Base Information

• Chemical Name: n-Benzylidene-4-biphenylamine
• CAS No.: 13924-28-2
• Molecular Formula: C19H15 N
• Molecular Weight: 257.335
• European Community (EC) Number: 653-784-7
• NSC Number: 158546
• Nikkaji Number: J1.902.752J
• Mol file: 13924-28-2.mol

Synonyms:n-benzylidene-4-biphenylamine;13924-28-2;NSC158546;SCHEMBL2592404;SCHEMBL5442784;AKOS001278919;AKOS030646669;NSC-158546;N-Benzylidene-[1,1'-biphenyl]-4-amine;N-[(E)-phenylmethylidene][1,1'-biphenyl]-4-amine;Z203055016

Chemical Property of n-Benzylidene-4-biphenylamine

Chemical Property:

• Vapor Pressure: 4.05E-07mmHg at 25°C
• Boiling Point: 427.6°Cat760mmHg
• Flash Point: 205°C
• Density: 0.99g/cm³
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 257.120449483
• Heavy Atom Count: 20
• Complexity: 289

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=NC2=CC=C(C=C2)C3=CC=CC=C3

Technology Process of n-Benzylidene-4-biphenylamine

There total 6 articles about n-Benzylidene-4-biphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

4-phenylalanine (92-67-1) + benzaldehyde (100-52-7) → N-benzylidene-4-phenylaniline (13924-28-2)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 5h; Heating;

DOI:10.1021/ma010736w

Reference yield:

phenylboronic acid (98-80-6) + N-benzylidene-4-bromoaniline (780-20-1) → N-benzylidene-4-phenylaniline (13924-28-2)

Guidance literature:

With potassium carbonate; [2-(Pd-Cl)-4,4'-dichlorobenzophenone oxime]2; In toluene; at 130 ℃; for 0.5h;

DOI:10.1021/jo025619t

Reference yield:

trans-4-Hydroxystilbene (6554-98-9) + 4-azidobiphenyl (31656-91-4) → N-benzylidene-4-phenylaniline (13924-28-2) + C19H15NO

Guidance literature:

With iron(II) chloride; In acetonitrile; at 100 ℃; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.9b03160

upstream raw materials:

4-phenylalanine

benzaldehyde

phenylboronic acid

N-benzylidene-4-bromoaniline

Downstream raw materials:

C₂₁H₂₁N

4-amino-4'-nitrobiphenyl

N-benzyl-[1,1'-biphenyl]-4-amine

Refernces

• 1、 Igbal. "-". . p. 2791. Retrieved 1972.
• 2、 Cheng, Biao,Lyu, Hairong,Quan, Yangjian,Xie, Zuowei. "Rhodium catalyzed multicomponent dehydrogenative annulation: one-step construction of isoindole derivatives". supporting information. p. 7930 - 7933. Retrieved 2021/08/17.
• 3、 William, Ronny,Wang, Siming,Ding, Feiqing,Arviana, Elise Nerissa,Liu, Xue-Wei. "Interrupted imino-nazarov cyclization of 1-aminopentadienyl cation and related cascade process". supporting information. p. 10742 - 10746. Retrieved 2015/05/13.