3-hydroxynaphthalene-2-carbaldehyde

Base Information

• Chemical Name: 3-hydroxynaphthalene-2-carbaldehyde
• CAS No.: 581-71-5
• Molecular Formula: C11H8 O2
• Molecular Weight: 172.183
• Hs Code.: 2912490090
• Mol file: 581-71-5.mol

Synonyms:2-Naphthaldehyde,3-hydroxy- (6CI,7CI,8CI); 2-Hydroxy-3-formylnaphthalene;2-Hydroxy-3-naphthaldehyde; 3-Formyl-2-naphthol; 3-Hydroxy-2-naphthaldehyde;3-Hydroxy-2-naphthalenecarboxaldehyde; NC 044; NSC 240729

Chemical Property of 3-hydroxynaphthalene-2-carbaldehyde

Chemical Property:

• Vapor Pressure: 0.000213mmHg at 25°C
• Melting Point: 98 °C
• Boiling Point: 317°C at 760 mmHg
• PKA: 7.77±0.40(Predicted)
• Flash Point: 134.3°C
• PSA: 37.30000
• Density: 1.288g/cm³
• LogP: 2.35790

Purity/Quality:

99%, ^*data from raw suppliers

3-Hydroxynaphthalene-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Hydroxynaphthalene-2-carbaldehyde is a derivative of Naphthalene (N345600), an abundant polycyclic aromatic hydrocarbon that is persistent, bioaccumulative, toxic and found in tobacco smoke and urban air.

Technology Process of 3-hydroxynaphthalene-2-carbaldehyde

There total 11 articles about 3-hydroxynaphthalene-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

tetramethyl 2,2',2'',2'''-((((1-(3-hydroxynaphthalen-2-yl)ethane-1,2-diyl)bis-(oxy))bis(2,1-phenyl-ene))bis(azanetriyl))tetraacetate → 2-Hydroxy-3-naphthaldehyde (581-71-5) + dimethyl 2,2'-((2-(2-(3-hydroxynaphthalen-2-yl)-2-oxoethoxy)phenyl)azanediyl)diacetate + dimethyl 2,2'-((2-hydroxyphenyl)azanediyl)diacetate + methyl 2-(2-oxo-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)acetate

Guidance literature:

In water; acetonitrile; for 0.0833333h; Quantum yield; Irradiation;

DOI:10.1039/c7cc02056b

Reference yield:

N-[(3-hydroxynaphthalen-2-yl)methoxy]benzenesulfonamide → benzenesulfonamide (98-10-2) + 2-Hydroxy-3-naphthaldehyde (581-71-5) + piloty's acid (599-71-3) + 3-hydroxymethyl-2-naphthol (30159-70-7) + phenylsulphinate anion (16722-50-2) + nitrosyl hydride

Guidance literature:

In aq. phosphate buffer; [D₃]acetonitrile; Kinetics; Irradiation; Inert atmosphere;

DOI:10.1002/ejoc.201800092

Reference yield:

N-[(3-hydroxynaphthalen-2-yl)methoxy]methanesulfonamide → 2-Hydroxy-3-naphthaldehyde (581-71-5) + methanesulfonamide (3144-09-0) + methanesulfinate (43633-03-0) + N-hydroxylmethanesulfonamide (50695-55-1) + 3-hydroxymethyl-2-naphthol (30159-70-7) + nitrosyl hydride

Guidance literature:

In aq. phosphate buffer; [D₃]acetonitrile; Kinetics; Irradiation; Inert atmosphere;

DOI:10.1002/ejoc.201800092

upstream raw materials:

(3-(ethoxymethoxy)naphthalen-2-yl)methanol

3-hydroxy-2-naphthoic acid methyl ester

C₁₅H₁₆O₄

Downstream raw materials:

naphtho[2,3-b]furan-2-yl(phenyl)methanone

(4-chlorophenyl)(naphtho[2,3-b]furan-2-yl)methanone

3',3'-dimethyl-1'-phenyl-1',3'-dihydro-spiro[benzo[f]chromene-3,2'-indole]

naphtho[2,3-b]furan-2-yl-phenyl ketone semicarbazone

Refernces

• 1、 Sutton, Mariia V.,McKinley, Matthew,Kulasekharan, Revathy,Popik, Vladimir V.. "Photo-cleavable analog of BAPTA for the fast and efficient release of Ca2+". . p. 5598 - 5601. Retrieved 2017/07/07.