3-(4-Chlorophenyl)dihydrofuran-2,5-dione

Base Information

• Chemical Name: 3-(4-Chlorophenyl)dihydrofuran-2,5-dione
• CAS No.: 776-52-3
• Molecular Formula: C10H7 Cl O3
• Molecular Weight: 210.6138
• Mol file: 776-52-3.mol

Synonyms:Succinicanhydride, (p-chlorophenyl)- (7CI,8CI); (4-Chlorophenyl)succinic anhydride; NSC151265

Chemical Property of 3-(4-Chlorophenyl)dihydrofuran-2,5-dione

Chemical Property:

• Vapor Pressure: 4.54E-06mmHg at 25°C
• Boiling Point: 383°Cat760mmHg
• Flash Point: 176.5°C
• PSA: 43.37000
• Density: 1.414g/cm³
• LogP: 1.89710

Purity/Quality:

98%min ^*data from raw suppliers

3-(4-chlorophenyl)oxolane-2,5-dione ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-43
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-Chlorophenyl)dihydrofuran-2,5-dione

There total 2 articles about 3-(4-Chlorophenyl)dihydrofuran-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ p-chlorophenylylsuccinic anhydride (776-52-3)

Guidance literature:

With acetic anhydride;

Reference yield:

→ p-chlorophenylylsuccinic anhydride (776-52-3)

Guidance literature:

<4-Chlor-phenyl>-bernsteinsaeure, Acetylchlorid, Thionylchlorid;

DOI:10.1021/jm00326a028

Reference yield: 44.0%

p-chlorophenylylsuccinic anhydride (776-52-3) → β-(R)-(p-chlorophenyl)-γ-butyrolactone (147224-51-9) + (S)-α-(4-chlorophenyl)-γ-butyrolactone + (R)-3-(4-Chloro-phenyl)-dihydro-furan-2-one

Guidance literature:

p-chlorophenylylsuccinic anhydride; With 2,2,2-trifluoroethanol; modified cinchona alkaloid (DHQD)2AQN; In diethyl ether; at -24 ℃;

With lithium triethylborohydride; In tetrahydrofuran; at 0 ℃; for 0.416667h;

DOI:10.1021/ja011766h

Downstream raw materials:

β-(R)-(p-chlorophenyl)-γ-butyrolactone

Refernces