5-(Dimethylamino)amylamine

Base Information

• Chemical Name: 5-(Dimethylamino)amylamine
• CAS No.: 3209-46-9
• Molecular Formula: C7H18 N2
• Molecular Weight: 130.233
• Hs Code.: 2921290000
• DSSTox Substance ID: DTXSID50392740
• Nikkaji Number: J3.570.355A
• Wikidata: Q82191124
• Mol file: 3209-46-9.mol

Synonyms:5-(Dimethylamino)amylamine;3209-46-9;N1,N1-dimethylpentane-1,5-diamine;N',N'-dimethylpentane-1,5-diamine;N,N-dimethylpentane-1,5-diamine;MFCD00047978;N,N-Dimethylpentane-1,5-diamine dihydrochloride;(5-aminopentyl)dimethylamine;5-(Dimethylamino)pentylamine;5-dimethylaminopentylamine;5-Dimethylamino-pentylamine;SCHEMBL363743;DTXSID50392740;ZQEQANWXEQSAGL-UHFFFAOYSA-N;AMY37685;AC2504;BBL104216;STL558080;AKOS002670911;1,5-Pentanediamine, N1,N1-dimethyl-;5-(Dimethylamino)amylamine, AldrichCPR;AS-10221;SY040702;FT-0619709;J3.570.355A;EN300-206253;J-018630

Chemical Property of 5-(Dimethylamino)amylamine

Chemical Property:

• Vapor Pressure: 0.888mmHg at 25°C
• Boiling Point: 180.6°Cat760mmHg
• PKA: 10.59±0.10(Predicted)
• Flash Point: 62.8°C
• PSA: 29.26000
• Density: g/cm³
• LogP: 1.37730
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 130.146998583
• Heavy Atom Count: 9
• Complexity: 52.9

Purity/Quality:

98%min ^*data from raw suppliers

5-(Dimethylamino)amylamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCCCCN

Technology Process of 5-(Dimethylamino)amylamine

There total 19 articles about 5-(Dimethylamino)amylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

2-N-[5-(N',N'-dimethylamino)pentyl]phthalimide (736922-42-2) → N,N-dimethyl-1,5-pentanediamine (3209-46-9)

Guidance literature:

With hydrazine hydrate; In ethanol; water; for 12h; Reflux;

DOI:10.1016/j.ejmech.2018.08.060

Reference yield:

1-(5-Dimethylamino-pentylamino)-2-methyl-propan-1-ol → isobutyraldehyde (78-84-2) + N,N-dimethyl-1,5-pentanediamine (3209-46-9)

Guidance literature:

In water; at 35 ℃; Equilibrium constant;

DOI:10.1021/jo00431a031

Reference yield:

5-(dimethylamino)-pentanenitrile (3209-45-8) → N,N-dimethyl-1,5-pentanediamine (3209-46-9)

Guidance literature:

With ammonia; nickel; at 100 ℃; Hydrogenation_.unter Druck;

DOI:10.1021/ja01641a045

upstream raw materials:

5-(dimethylamino)-pentanenitrile

5-dimethylamino-pent-3-enenitrile

N-(5-dimethylamino-pentyl)-benzamide

2-N-[5-(N',N'-dimethylamino)pentyl]phthalimide

Downstream raw materials:

Acridine-4-carboxylic acid (5-dimethylamino-pentyl)-amide

2-Phenyl-quinoline-8-carboxylic acid (5-dimethylamino-pentyl)-amide; hydrochloride

N-(5-dimethylamino-pentyl)-benzene-1,2-diamine

2,4-bis(4'-fluorophenethylamino)-6-(5'-(N,N-dimethylamino)pentylamino)-1,3,5-triazine

Refernces

• 1、 Patel, Dushyant V.,Patel, Nirav R.,Kanhed, Ashish M.,Patel, Sagar P.,Sinha, Anshuman,Kansara, Deep D.,Mecwan, Annie R.,Patel, Sarvangee B.,Upadhyay, Pragnesh N.,Patel, Kishan B.,Shah, Dharti B.,Prajapati, Navnit K.,Murumkar, Prashant R.,Patel, Kirti V.,Yadav, Mange Ram. "Novel Multitarget Directed Triazinoindole Derivatives as Anti-Alzheimer Agents". . p. 3635 - 3661. Retrieved 2019/08/20.
• 2、 Zhu, Yimin,Drueckhammer, Dale G.. "Transition state modeling and catalyst design for hydrogen bond-stabilized enolate formation". . p. 7755 - 7760. Retrieved 2007/10/03.