L-GLUCONO-1,5-LACTONE

Base Information

• Chemical Name: L-GLUCONO-1,5-LACTONE
• CAS No.: 52153-09-0
• Molecular Formula: C6H10 O6
• Molecular Weight: 178.142
• Hs Code.: 2932999099
• Mol file: 52153-09-0.mol

Synonyms:L-Glucono-1,5-lactone;L-Gluconolactone

Chemical Property of L-GLUCONO-1,5-LACTONE

Chemical Property:

• Melting Point: 142-144 °C(lit.)
• Refractive Index: 1.5860 (estimate)
• Boiling Point: 446.4°Cat760mmHg
• PKA: 12.13±0.70(Predicted)
• Flash Point: 192.3°C
• PSA: 107.22000
• Density: 1.72g/cm³
• LogP: -3.01320
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Water (Slightly, Sonicated)

Purity/Quality:

98%Min ^*data from raw suppliers

L-Glucono-1,5-lactone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-Glucono-1,5-lactone is the lactone derivative of L-gluconic acid.

Technology Process of L-GLUCONO-1,5-LACTONE

There total 4 articles about L-GLUCONO-1,5-LACTONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.5%

methyl 2,3-O-isopropylidene-β-D-gulofuranosiduronic acid (90405-08-6) → L-glucono-1,5-lactone (52153-09-0,1335-57-5,4253-68-3)

Guidance literature:

With Dowex 50W-X₈ H⁺ form; hydrogen; nickel; In water; 1.) 60 to 70 deg C, 45 h; 2.) r.t., 18 h;

Reference yield:

L-allonic acid (740753-96-2) → L-allonic acid-5-lactone (90-80-2,7506-65-2,10366-75-3,15892-28-1,32746-79-5,52153-09-0,52393-78-9,110115-45-2,120523-34-4,124819-01-8,124915-65-7,1335-57-5,4253-68-3)

Guidance literature:

With ethanol; schnelles Eindampfen unter vermindertem Druck und Behandeln des Rueckstands mit wasserfreiem Aethanol;

Reference yield:

L-gluconic acid ; potassium-compound (1022160-11-7) → L-glucono-1,5-lactone (52153-09-0,1335-57-5,4253-68-3) + γ lactone of/the/ l-gluconic acid (74464-44-1)

Guidance literature:

With hydrogenchloride; In water; at 50 ℃; pH=2.5;

upstream raw materials:

L-allonic acid

methyl 2,3-O-isopropylidene-β-D-gulofuranosiduronic acid

L-gluconic acid ; potassium-compound

potassium gluconate

Downstream raw materials:

L-glucose

L-mannonic γ-lactone

Refernces

• 1、 -. "PROCESS FOR PREPARATION OF ALDONIC ACIDS AND DERIVATIVES THEREOF". Page/Page column 15-16. . Retrieved 2008/12/05.