Ferrous bisglycinate

Base Information

• Chemical Name: Ferrous bisglycinate
• CAS No.: 20150-34-9
• Molecular Formula: C4H8FeN2O4
• Molecular Weight: 203.966
• European Community (EC) Number: 606-444-7
• UNII: SFW1D987QV
• DSSTox Substance ID: DTXSID30173978
• Nikkaji Number: J898.250C
• Wikidata: Q27289189
• RXCUI: 1102188
• Mol file: 20150-34-9.mol

Synonyms:ferrous bisglycinate

Chemical Property of Ferrous bisglycinate

Chemical Property:

• Vapor Pressure: 0-0Pa at 20-25℃
• Boiling Point: 240.9 °C at 760 mmHg
• Flash Point: 99.5 °C
• PSA: 132.30000
• Density: 1.898 at 20℃
• LogP: -3.21190
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: Aqueous Acid (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 203.983342
• Heavy Atom Count: 11
• Complexity: 37.4

Purity/Quality:

99% ^*data from raw suppliers

FerrousBisglycinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(=O)[O-])N.C(C(=O)[O-])N.[Fe+2]
• Recent ClinicalTrials: Potential Harms of Untargeted Iron Supplementation in Cambodia Where Iron Deficiency is Not the Cause of Anemia
• Recent EU Clinical Trials: JERNPROFYLAKSE TIL GRAVIDE – ER FERROAMINOCHELAT MERE EFFEKTIVT END FERROSULFAT?
• Uses: Nutraceutical Ferrous Bisglycinate is an iron-amio acid chelate. In this the iron is protected from the action of absorption inhibitors by being bound to the amino acid and glycine. Ferrous bisglycinate is the major amino acid chelate produced commercially, although ferrous trisglycinate and ferric glycinate are also available. A patented ferrous bisglycinate compound, manufactured by Albion Laboratories, Utah, USA, has been used in most published studies. The chelate is reported to be formed by two glycine molecules combining with ferrous iron in a double heterocyclic ring structure. Evidence would suggest that iron is protected from inhibitors by the structure, since iron absorption is one to 3.5 times higher than from ferrous sulfate when added to bread rolls and milk products containing inhibitors such as phytate and calcium. Ferrous bisglycinate is more bioavailable than ferrous trisglycinate. Ferrous Bisglycinate is used in the fortification of infant formulations and foods.

Technology Process of Ferrous bisglycinate

There total 2 articles about Ferrous bisglycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

iron(II) oxide (1345-25-1) + sodium glycinate (6000-44-8) → ferrous glycinate (20150-34-9)

Guidance literature:

With citric acid; In water; at 55 - 60 ℃; for 1h;

Reference yield:

iron sulfide + glycine (56-40-6) → ferrous glycinate (20150-34-9)

Guidance literature:

In solid; byproducts: H2S; 180°C, in air; washed on filter with water, elem. anal.;

Reference yield:

ferrous glycinate (20150-34-9) → iron (7439-89-6)

Guidance literature:

In neat (no solvent); thermal decompn., in closed crucible, limited supply of air, 420°C; small quantities of the oxides formed;

upstream raw materials:

iron(II) oxide

sodium glycinate

glycine

Downstream raw materials:

iron

Refernces