3,5-DIIODO-4-HYDROXYPHENYLPYRUVIC ACID

Base Information

• Chemical Name: 3,5-DIIODO-4-HYDROXYPHENYLPYRUVIC ACID
• CAS No.: 780-00-7
• Molecular Formula: C9H6 I2 O4
• Molecular Weight: 431.953
• Mol file: 780-00-7.mol

Synonyms:Pyruvicacid, (4-hydroxy-3,5-diiodophenyl)- (6CI,7CI,8CI);(4-Hydroxy-3,5-diiodophenyl)pyruvic acid; 3,5-Diiodo-4-hydroxyphenylpyruvicacid

Chemical Property of 3,5-DIIODO-4-HYDROXYPHENYLPYRUVIC ACID

Chemical Property:

• Vapor Pressure: 3.17E-07mmHg at 25°C
• Melting Point: 215-222°C
• Boiling Point: 403.2°C at 760 mmHg
• PKA: 2.27±0.54(Predicted)
• Flash Point: 197.7°C
• PSA: 74.60000
• Density: 2.495g/cm³
• LogP: 1.79760
• Storage Temp.: -20?C Freezer
• Solubility.: Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98%Min ^*data from raw suppliers

3,5-Diiodo-4-hydroxyphenylpyruvic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3,5-Diiodo-4-hydroxyphenylpyruvic Acid (cas# 780-00-7) is a compound useful in organic synthesis.

Technology Process of 3,5-DIIODO-4-HYDROXYPHENYLPYRUVIC ACID

There total 3 articles about 3,5-DIIODO-4-HYDROXYPHENYLPYRUVIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-3,5-diiodobenzaldehyde (1948-40-9) → (4-hydroxy-3,5-diiodo-phenyl)-pyruvic acid (780-00-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate; acetic acid anhydride

With sodium acetate; acetic anhydride;

Reference yield:

4-(4-acetoxy-3,5-diiodo-benzylidene)-2-methyl-4H-oxazol-5-one (93087-37-7) → (4-hydroxy-3,5-diiodo-phenyl)-pyruvic acid (780-00-7)

Guidance literature:

Reference yield:

→ (4-hydroxy-3,5-diiodo-phenyl)-pyruvic acid (780-00-7)

Guidance literature:

DOI:10.1021/jo01065a070

upstream raw materials:

4-(4-acetoxy-3,5-diiodo-benzylidene)-2-methyl-4H-oxazol-5-one

4-hydroxy-3,5-diiodobenzaldehyde

Downstream raw materials:

4-hydroxy-3,5-diiodobenzaldehyde

2,6-diiodo-p-benzoquinone

4-hydroxy-3,5-diiodo-mandelic acid