Triciribine phosphate

Base Information

• Chemical Name: Triciribine phosphate
• CAS No.: 61966-08-3
• Molecular Formula: C13H17N6O7P
• Molecular Weight: 400.29
• UNII: 5L5GE3DV88
• DSSTox Substance ID: DTXSID30210993
• Nikkaji Number: J69.483E
• Wikidata: Q27262513
• NCI Thesaurus Code: C1262
• Metabolomics Workbench ID: 154996
• ChEMBL ID: CHEMBL462018
• Mol file: 61966-08-3.mol

Synonyms:1,4,5,6,8-pentaazaacenaphthylene-3-amino-1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl 5'-phosphate ester;NSC 280594;NSC-280594;TCN-monophosphate;TCN-P;TCNP;triciribine phosphate

Chemical Property of Triciribine phosphate

Chemical Property:

• Vapor Pressure: 2.1E-29mmHg at 25°C
• Refractive Index: 1.924
• Boiling Point: 832.8 °C at 760 mmHg
• Flash Point: 457.4 °C
• PSA: 200.81000
• Density: 2.23 g/cm³
• LogP: -0.79010
• XLogP3: -3.3
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 4
• Exact Mass: 400.08963390
• Heavy Atom Count: 27
• Complexity: 663

Purity/Quality:

97% ^*data from raw suppliers

Tricyclic nucleoside phosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C2=NC=NC3=C2C(=CN3C4C(C(C(O4)COP(=O)(O)O)O)O)C(=N1)N
• Isomeric SMILES: CN1C2=NC=NC3=C2C(=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(O)O)O)O)C(=N1)N
• Recent ClinicalTrials: PTX-200, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patients With Stage IIB-IV Breast Cancer
• Uses: Triciribine phosphate is an Akt activation inhibitor that inhibits Akt phosphorylation by binding to the pleckstrin homology (PH) domain of the Akt and blocking its recruitment to the plasma membrane.