N-benzylstearamide

Base Information

• Chemical Name: N-benzylstearamide
• CAS No.: 5327-45-7
• Molecular Formula: C25H43NO
• Molecular Weight: 373.623
• Hs Code.: 2924299090
• NSC Number: 3333
• DSSTox Substance ID: DTXSID60277650
• Nikkaji Number: J1.329.103I
• Wikidata: Q82008953
• ChEMBL ID: CHEMBL2415104
• Mol file: 5327-45-7.mol

Synonyms:n-benzyloctadecanamide;N-benzylstearamide;5327-45-7;NSC 3333;Octadecanamide, N-(phenylmethyl)-;N-octadecanoyl benzylamine;CHEMBL2415104;NSC3333;Stearamide, N-benzyl-;Octadecanamide, N-benzyl-;N-(Phenylmethyl)octadecanamide;SCHEMBL2088173;DTXSID60277650;HY-N4188;NSC-3333;BDBM50438775;LMFA08020156;AKOS028111139;AC-34554;MS-26033;CS-0032381;F82179;RMA042LEX, RT: 28.252 min, Maca, Lepidium meyenii, Mega Market Rockville

Chemical Property of N-benzylstearamide

Chemical Property:

• Vapor Pressure: 3.97E-11mmHg at 25°C
• Refractive Index: 1.489
• Boiling Point: 525.317 °C at 760 mmHg
• Flash Point: 326.346 °C
• PSA: 29.10000
• Density: 0.914 g/cm³
• LogP: 7.95520
• XLogP3: 9.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 18
• Exact Mass: 373.334464995
• Heavy Atom Count: 27
• Complexity: 322

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)NCC1=CC=CC=C1

Technology Process of N-benzylstearamide

There total 10 articles about N-benzylstearamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

stearic acid (57-11-4) + benzyl azide (622-79-7) → N-benzyl-octadecanamide (5327-45-7)

Guidance literature:

With 2,2'-dipyridyldiselenide; trimethylphosphane; In toluene; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/jo802825e

Reference yield: 93.0%

stearic acid (57-11-4) + benzylamine (100-46-9) → N-benzyl-octadecanamide (5327-45-7)

Guidance literature:

With Bromotrichloromethane; 4-(diphenylphosphino)-benzyltrimethylammonium bromide; triethylamine; In tetrahydrofuran; dichloromethane; at 60 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tet.2013.03.021

Reference yield: 88.0%

distearoyl diselenide (65212-12-6) + benzylamine (100-46-9) → N-benzyl-octadecanamide (5327-45-7)

Guidance literature:

In benzene; at 25 ℃; for 0.166667h;

upstream raw materials:

Stearoyl chloride

benzylamine

distearoyl diselenide

1-Pyrrol-1-yl-octadecan-1-one

Downstream raw materials:

stearic acid

benzylamine

Refernces

• 1、 Singh, Nalin,Barnych, Bogdan,Morisseau, Christophe,Wagner, Karen M.,Wan, Debin,Takeshita, Ashley,Pham, Hoang,Xu, Ting,Dandekar, Abhaya,Liu, Jun-Yan,Hammock, Bruce D.. "N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain". . p. 3689 - 3697. Retrieved 2021/01/09.
• 2、 Kothandapani, Jagatheeswaran,Ganesan, Asaithampi,Ganesan, Subramaniapillai Selva. "Nano-Magnetic Sulfonic Acid Catalyzed Facile Synthesis of Diverse Amide Derivatives". . p. 685 - 692. Retrieved 2017/01/25.