2,2,3,3-Tetrafluoropropyl 2-fluoroacrylate

Base Information

• Chemical Name: 2,2,3,3-Tetrafluoropropyl 2-fluoroacrylate
• CAS No.: 96250-37-2
• Molecular Formula: C₆H₅F₅O₂
• Molecular Weight: 204.097
• Hs Code.: 2916190090
• European Community (EC) Number: 671-773-5
• DSSTox Substance ID: DTXSID60242181
• Nikkaji Number: J360.165J
• Wikidata: Q83125814
• Mol file: 96250-37-2.mol

Synonyms:2,2,3,3-Tetrafluoropropyl 2-fluoroacrylate;96250-37-2;2,2,3,3-tetrafluoropropyl 2-fluoroprop-2-enoate;Monomer FN-1;BRN 3540424;2-Propenoic acid, 2-fluoro-, 2,2,3,3-tetrafluoropropyl ester;2,2,3,3-Tetrafluoropropyl 2-fluoro-2-propenoate;2,2,3,3-tetrafluoropropyl-2'-fluoroacrylate;SCHEMBL2526807;DTXSID60242181;OOPSTBSKXWPLKJ-UHFFFAOYSA-N;5,5,6,6-tetrafluorohex-2-enoate;MFCD01696283;AKOS017342867;FS-5481;LS-123643;2,2,3,3-tetrafluoropropyl-2-fluoroacrylate;FT-0642322;A845571;2-Fluoroacrylic acid 2,2,3,3-tetrafluoropropyl ester;2-Fluoro-2-propenoic acid 2,2,3,3-tetrafluoropropyl ester;2-Propenoic acid,2-fluoro-,2,2,3,3-tetrafluoropropyl ester

Chemical Property of 2,2,3,3-Tetrafluoropropyl 2-fluoroacrylate

Chemical Property:

• Vapor Pressure: 4.93mmHg at 25°C
• Refractive Index: 1.36
• Boiling Point: 145.1 °C at 760 mmHg
• Flash Point: 47.2 °C
• PSA: 26.30000
• Density: 1.328 g/cm³
• LogP: 1.91320
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 204.02097021
• Heavy Atom Count: 13
• Complexity: 213

Purity/Quality:

98%min ^*data from raw suppliers

2,2,3,3-Tetrafluoropropyl-2'-fluoroacrylate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=C(C(=O)OCC(C(F)F)(F)F)F

Technology Process of 2,2,3,3-Tetrafluoropropyl 2-fluoroacrylate

There total 5 articles about 2,2,3,3-Tetrafluoropropyl 2-fluoroacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,2,3,3-tetrafluoropropyl 2,3-difluoropropionate (142337-37-9) → 2,2,3,3-tetrafluoropropyl 2-fluoroacrylate (96250-37-2)

Guidance literature:

With triethylamine;

DOI:10.1016/S0022-1139(00)83648-9

Reference yield: 80.0%

3-Bromo-2-chloro-2-fluoro-propionic acid 2,2,3,3-tetrafluoro-propyl ester → 2,2,3,3-tetrafluoropropyl 2-fluoroacrylate (96250-37-2)

Guidance literature:

With zinc;

DOI:10.1016/S0022-1139(00)83648-9

Reference yield:

2,2,3,3-tetrafluoropropyl-2,3-dibromopropionate (142337-36-8) → 2,2,3,3-tetrafluoropropyl 2-fluoroacrylate (96250-37-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / bromine trifluoride, 1 mol percent tin tetrachloride / 1,1,2-trichloro-1,2,2-trifluoro-ethane / 2.5 h / 20 - 30 °C

2: 90 percent / triethylamine / CH₂Cl₂ / 20 - 40 °C

With bromine trifluoride; tin(IV) chloride; triethylamine; In dichloromethane; 1,1,2-Trichloro-1,2,2-trifluoroethane;

upstream raw materials:

2,2,3,3-tetrafluoropropyl 2,3-difluoropropionate

acrylate de trihydro-1,1,3 tetrafluoropropyle

2,2,3,3-tetrafluoropropyl-2,3-dibromopropionate

Refernces

• 1、 Kartashov, A. V.,Chuvatkin, N. N.,Boguslavskaya, L. S.. "REACTIONS OF HALOGEN FLUORIDES XII. REACTION OF BROMINE TRIFLUORIDE WITH BROMINE-CONTAINING ESTERS. A NEW METHOD FOR THE SYNTHESIS OF FLUOROALKYL 2-FLUOROACRYLATES". . p. 2243 - 2248. Retrieved 2007/10/02.