Technology Process of 16alpha,17,21-trihydroxypregna-4,9(11)-diene-3,20-dione 21-acetate
There total 1 articles about 16alpha,17,21-trihydroxypregna-4,9(11)-diene-3,20-dione 21-acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
21-acetoxy-pregna-4,9(11),16-triene-3,20-dinone;
With
formic acid;
In
acetone;
at -5 - 0 ℃;
for 0.0833333h;
With
potassium permanganate;
In
water; acetone;
at -5 - 0 ℃;
for 0.166667h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine
2: aqueous HClO4; dioxane
3: potassium acetate; ethanol / Behandeln einer Loesung des Reaktionsprodukts in Pyridin mit Acetanhydrid
4: CHCl3; HF
5: mit Hilfe von Nocardia corallina
With
1,4-dioxane; pyridine; perchloric acid; ethanol; chloroform; hydrogen fluoride; potassium acetate;
DOI:10.1021/ja01516a044
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine
2: aqueous HClO4; dioxane
3: potassium acetate; ethanol / Behandeln einer Loesung des Reaktionsprodukts in Pyridin mit Acetanhydrid
4: CHCl3; HF
5: methanol. sodium methylate
With
1,4-dioxane; pyridine; perchloric acid; ethanol; chloroform; hydrogen fluoride; sodium methylate; potassium acetate;
DOI:10.1021/ja01516a044
