5-AMINOBENZENE-1,3-DIOL HYDROCHLORIDE

Base Information

• Chemical Name: 5-AMINOBENZENE-1,3-DIOL HYDROCHLORIDE
• CAS No.: 6318-56-5
• Molecular Formula: C6H7NO2^.HCl
• Molecular Weight: 161.588
• Hs Code.: 2922299090
• Mol file: 6318-56-5.mol

Synonyms:1,3-Benzenediol,5-amino-, hydrochloride (9CI);5-Aminobenzene-1,3-diol hydrochloride;

Chemical Property of 5-AMINOBENZENE-1,3-DIOL HYDROCHLORIDE

Chemical Property:

• Melting Point: 300 °C
• PSA: 66.48000
• LogP: 2.06320
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Aminobenzene-1,3-diolHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-AMINOBENZENE-1,3-DIOL HYDROCHLORIDE

There total 1 articles about 5-AMINOBENZENE-1,3-DIOL HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

3,5-dihydroxyphenol (108-73-6) → 5-aminobenzene-1,3-diol hydrochloride (6318-56-5)

Guidance literature:

3,5-dihydroxyphenol; With ammonium hydroxide; In water; at 15 - 25 ℃; for 24h; Inert atmosphere;

With hydrogenchloride; In water; Cooling with ice;

Reference yield: 72.0%

tert-butyldimethylsilyl chloride (18162-48-6) + 5-aminobenzene-1,3-diol hydrochloride (6318-56-5) → 3,5-bis(tert-butyldimethylsilyloxy)aniline (1398702-11-8)

Guidance literature:

With 1H-imidazole; In tetrahydrofuran; at 25 ℃; for 37h; Cooling with ice; Inert atmosphere;

Reference yield:

3-(triethoxypropyl) isocyanate (24801-88-5) + 5-aminobenzene-1,3-diol hydrochloride (6318-56-5) → C16H28N2O6Si

Guidance literature:

In acetonitrile; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1016/j.jorganchem.2017.11.027

upstream raw materials:

3,5-dihydroxyphenol

Downstream raw materials:

5-azidobenzene-1,3-diol

methyl (3-azido-5-hydroxyphenoxy)acetate

(3-azido-5-methoxyphenoxy)acetic acid

methyl (3-azido-5-methoxyphenoxy)acetate

Refernces

• 1、 Müller, Jonas I.,Kusserow, Kalina,Hertrampf, Gesa,Pavic, Aleksandar,Nikodinovic-Runic, Jasmina,Gulder, Tobias A. M.. "Synthesis and initial biological evaluation of myxocoumarin B". supporting information. p. 1966 - 1969. Retrieved 2019/02/20.
• 2、 -. "SUBSTITUTED AROMATIC COMPOUND, HYDROGELATION AGENT, HYDROGEL, AND METHOD FOR GELATING AQUEOUS SAMPLE". Paragraph 0159; 0160; 0161. . Retrieved 2014/01/23.