2-(biphenyl-4-yl)-2-oxoethyl heptanoate

Base Information

• Chemical Name: 2-(biphenyl-4-yl)-2-oxoethyl heptanoate
• CAS No.: 4376-35-6
• Molecular Formula: C₂₁H₂₄O₃
• Molecular Weight: 324.42
• Mol file: 4376-35-6.mol

Synonyms:Heptanoicacid, ester with 2-hydroxy-4'-phenylacetophenone (7CI,8CI); NSC 406822;p-Phenylphenacyl heptanoate

Chemical Property of 2-(biphenyl-4-yl)-2-oxoethyl heptanoate

Chemical Property:

• Vapor Pressure: 1.44E-08mmHg at 25°C
• Boiling Point: 457.8°Cat760mmHg
• Flash Point: 199.1°C
• Density: 1.062g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(biphenyl-4-yl)-2-oxoethyl heptanoate

There total 4 articles about 2-(biphenyl-4-yl)-2-oxoethyl heptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Bromo-4'-phenylacetophenone (135-73-9) → enanthic acid p-phenylphenacylester (4376-35-6)

Guidance literature:

With ethanol;

DOI:10.1002/hlca.19470300725 DOI:10.1021/ja01372a045

Reference yield:

oenanthic acid (111-14-8) + 2-Bromo-4'-phenylacetophenone (135-73-9) → enanthic acid p-phenylphenacylester (4376-35-6)

Guidance literature:

oenanthic acid; With caesium carbonate; In methanol; at 20 ℃;

2-Bromo-4'-phenylacetophenone; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmcl.2004.04.059

Reference yield:

biphenyl-4-acetaldehyde (92-91-1) → enanthic acid p-phenylphenacylester (4376-35-6)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; bromine / 45 - 50 °C

2: aqueous ethanol

With ethanol; bromine; acetic acid;

DOI:10.1021/ja01372a045

upstream raw materials:

2-Bromo-4'-phenylacetophenone

oenanthic acid

biphenyl-4-acetaldehyde

biphenyl

Refernces