2-FURANOL,TETRAHYDRO-2-METH

Base Information

• Chemical Name: 2-FURANOL,TETRAHYDRO-2-METH
• CAS No.: 7326-46-7
• Molecular Formula: C5H10 O2
• Molecular Weight: 102.133
• DSSTox Substance ID: DTXSID10993994
• Nikkaji Number: J100.756D
• Mol file: 7326-46-7.mol

Synonyms:2-Hydroxy-2-methyltetrahydrofuran;Tetrahydro-2-methyl-2-furanol

Chemical Property of 2-FURANOL,TETRAHYDRO-2-METH

Chemical Property:

• Vapor Pressure: 1.12mmHg at 25°C
• Boiling Point: 155.1°C at 760 mmHg
• PKA: 13.28±0.20(Predicted)
• Flash Point: 60.6°C
• PSA: 29.46000
• Density: 1.073g/cm³
• LogP: 0.50530
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 102.068079557
• Heavy Atom Count: 7
• Complexity: 72.5

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CCCO1)O

Technology Process of 2-FURANOL,TETRAHYDRO-2-METH

There total 16 articles about 2-FURANOL,TETRAHYDRO-2-METH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

Cyclopropyl methyl ketone (765-43-5) → 2-Methyl-tetrahydro-furan-2-ol (7326-46-7) + 5-(2-methyl-tetrahydrofurn-2-yloxy)-pentan-2-one (7326-47-8) + 5-Hydroxy-2-pentanone (1071-73-4) + 6-oxaundeca-2,10-dione (93677-66-8)

Guidance literature:

With copper(ll) bromide; In diethyl ether; water; at 180 ℃; for 6h;

DOI:10.1023/A:1014010907818

Reference yield:

1,4-Pentanediol (626-95-9) → 5-methyl-tetrahydro-furan-2-ol (18545-25-0) + 2-Methyl-tetrahydro-furan-2-ol (7326-46-7) + 4-hydroxypentanal (44601-24-3) + 5-Hydroxy-2-pentanone (1071-73-4) + levulinic acid (123-76-2) + 5-methyl-dihydro-furan-2-one (108-29-2)

Guidance literature:

With oxygen; In water; acetonitrile; at 60 ℃; Product distribution; Mechanism; Irradiation; various metal oxide semiconductor powders;

DOI:10.1021/jo00277a021

Reference yield:

furfural (98-01-1) → Tetrahydrofurfuryl alcohol (97-99-4) + 2-Methyl-tetrahydro-furan-2-ol (7326-46-7) + 1,2-pentanediol (5343-92-0)

Guidance literature:

With Ni₃Sn₄; hydrogen; In ethanol; water; at 20 - 179.84 ℃; for 12h; Autoclave;

DOI:10.1039/c8gc03938k

upstream raw materials:

1,4-Pentanediol

Cyclopropyl methyl ketone

5-hydroxymethyl-2-furfuraldehyde

2-methylfuran

Downstream raw materials:

tetrahydro-2-furancarboxylic acid

Refernces

• 1、 Bugnola, Marco,Shen, Kaiji,Haviv, Eynat,Neumann, Ronny. "Reductive Electrochemical Activation of Molecular Oxygen Catalyzed by an Iron-Tungstate Oxide Capsule: Reactivity Studies Consistent with Compound i Type Oxidants". . p. 4227 - 4237. Retrieved 2020/05/05.
• 2、 Hu, Xun,Westerhof, Roel J. M.,Wu, Liping,Dong, Dehua,Li, Chun-Zhu. "Upgrading biomass-derived furans via acid-catalysis/hydrogenation: The remarkable difference between water and methanol as the solvent". . p. 219 - 224. Retrieved 2018/04/16.