1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE

Base Information

• Chemical Name: 1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE
• CAS No.: 30186-41-5
• Molecular Formula: C11H8 N2 O3
• Molecular Weight: 216.196
• Hs Code.: 2933990090
• Mol file: 30186-41-5.mol

Synonyms:Pyrrole-2-carboxaldehyde,1-(p-nitrophenyl)- (7CI,8CI); 1-(4-Nitrophenyl)pyrrole-2-carboxaldehyde;N-(p-Nitrophenyl)pyrrole-2-carboxaldehyde

Chemical Property of 1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE

Chemical Property:

• Vapor Pressure: 1.46E-06mmHg at 25°C
• Melting Point: 166.5 °C
• Boiling Point: 398.6°Cat760mmHg
• PKA: -10.20±0.70(Predicted)
• Flash Point: 194.8°C
• PSA: 67.82000
• Density: 1.3g/cm³
• LogP: 2.72120

Purity/Quality:

98%Min ^*data from raw suppliers

1-(4-Nitrophenyl)-1H-pyrrole-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE

There total 6 articles about 1-(4-NITROPHENYL)-1H-PYRROLE-2-CARBALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

furfural (98-01-1) + 4-nitro-aniline (100-01-6,104810-17-5) → 1-(4-nitrophenyl)pyrrole-2-carbaldehyde (30186-41-5)

Guidance literature:

With hydrogenchloride; In ethanol; for 2h; Heating;

DOI:10.1007/BF00479906

Reference yield: 80.0%

(1Z,3E)-1-(4-Nitro-phenylamino)-5-[(E)-4-nitro-phenylimino]-penta-1,3-dien-2-ol; hydrochloride → 1-(4-nitrophenyl)pyrrole-2-carbaldehyde (30186-41-5) + 2,4-bis(4-nitrophenylamino)-2-cyclopentenone (79863-21-1)

Guidance literature:

With hydrogenchloride; In ethanol; for 0.25h;

Reference yield:

2-pyrrole aldehyde (1003-29-8,254729-95-8) + 4-Fluoronitrobenzene (350-46-9,178603-76-4) → 1-(4-nitrophenyl)pyrrole-2-carbaldehyde (30186-41-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 120h;

DOI:10.1016/j.dyepig.2009.10.019

upstream raw materials:

furfural

4-nitro-aniline

2-pyrrole aldehyde

4-Fluoronitrobenzene

Downstream raw materials:

5-[1-(4-nitro-phenyl)-pyrrol-2-ylmethylene]-2-thioxo-thiazolidin-4-one

5-methyl-4-[1-(4-nitro-phenyl)-pyrrol-2-ylmethylene]-2-phenyl-2,4-dihydro-pyrazol-3-one

{Hydroxy-[1-(4-nitro-phenyl)-1H-pyrrol-2-yl]-methyl}-phosphonic acid diisopropyl ester

(3-Methoxy-phenyl)-[1-[1-(4-nitro-phenyl)-1H-pyrrol-2-yl]-meth-(E)-ylidene]-amine

Refernces

• 1、 Pina, M. del' K.,Budylin, V. A.,Rodriges, M.,Terent'ev, P. B.,Bundel', Yu. G.. "SYNTHESIS AND SPECTRAL PROPERTIES OF 1-ARYL-2-FORMYLPYRROLES". . p. 142 - 146. Retrieved 2007/10/02.
• 2、 Baum, E.,Goldovskaya, T. E.,Kul'nevich, V. G.,Maiorova, O. V.. "PREPARATION OF 1-(4-NITROPHENYL)-2-FORMYLPYRROLE FROM FURFURAL". . p. 786 - 790. Retrieved 2007/10/02.