1-Amino-2-propanethiol hydrochloride

Base Information

• Chemical Name: 1-Amino-2-propanethiol hydrochloride
• CAS No.: 4146-16-1
• Molecular Formula: C3H9 N S . Cl H
• Molecular Weight: 0
• Hs Code.: 2930909090
• NSC Number: 161608
• Mol file: 4146-16-1.mol

Synonyms:1-Amino-2-propanethiol hydrochloride;1-aminopropane-2-thiol hydrochloride;4146-16-1;1-aminopropane-2-thiol;hydrochloride;NSC 161608;2-Propanethiol, 1-amino-, hydrochloride;C(C)(S)CN;SCHEMBL4148312;2-mercaptopropylamine hydrochloride;1-aminopropane-2-thiolhydrochloride;1-amino-2-Propanethiol,hydrochloride;NSC161608;AKOS026705685;NSC-161608;LS-120993;CS-0231499;EN300-108561;F8888-7023

Chemical Property of 1-Amino-2-propanethiol hydrochloride

Chemical Property:

• Melting Point: 90-91 °C(Solv: isopropanol (67-63-0))
• Boiling Point: 137.6°Cat760mmHg
• Flash Point: 37°C
• PSA: 64.82000
• Density: 0.948g/cm³
• LogP: 1.76570
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 127.0222482
• Heavy Atom Count: 6
• Complexity: 22.9

Purity/Quality:

99%, ^*data from raw suppliers

1-aminopropane-2-thiolhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CN)S.Cl

Technology Process of 1-Amino-2-propanethiol hydrochloride

There total 4 articles about 1-Amino-2-propanethiol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2,5-dimethylthiazoline (4146-19-4) → 1-amino-2-propanethiol hydrochloride (4146-16-1)

Guidance literature:

With hydrogenchloride; Heating;

DOI:10.1515/znb-1987-0317

Reference yield: 69.0%

5-methylthiazolidine-2-thione (1437-90-7) → 1-amino-2-propanethiol hydrochloride (4146-16-1)

Guidance literature:

With hydrogenchloride; Heating;

DOI:10.1515/znb-1987-0317

Reference yield:

S-1-(tert-butoxycarbonylamino)propan-2-yl ethanethioate → 1-amino-2-propanethiol hydrochloride (4146-16-1)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 3h;

upstream raw materials:

2,5-dimethylthiazoline

5-methylthiazolidine-2-thione

Downstream raw materials:

2-Isopropyl-5-methyl 1,3-thiazolane

1-<4-Nitro-benzamino>-2-<(4-nitro-benzoyl)-mercapto>-propan

(+)-5-Methyl-2-phenyl-thiazolidin

(+/-)-5-Methyl-2-phenyl-thiazolidin

Refernces

• 1、 Wu, Shao-Yong,Hirashima, Akinori,Takeya, Ryuko,Eto, Morifusa. "Synthesis and Insecticidal Activity of Oxazaphospholidines, Oxathiaphospholanes, and Thiazaphospholidines". . p. 2911 - 2918. Retrieved 2007/10/02.