Dormin

Base Information

• Chemical Name: Dormin
• CAS No.: 14375-45-2
• Deprecated CAS: 20304-07-8
• Molecular Formula: C₁₅H₂₀O₄
• Molecular Weight: 264.321
• Hs Code.: 29189900
• European Community (EC) Number: 244-319-5
• NSC Number: 759648
• UNII: 3B18Y5RNGK
• DSSTox Substance ID: DTXSID1030604
• Nikkaji Number: J2.004.409H
• Wikipedia: Abscisic_acid
• Wikidata: Q27109429
• Metabolomics Workbench ID: 53871
• ChEMBL ID: CHEMBL379808
• Mol file: 14375-45-2.mol

Synonyms:2,4-Pentadienoic acid, 5-(1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-, (S-(Z,E))-;Abscisic Acid;Abscisic Acid Monoammonium Salt, (R)-Isomer;Abscisic Acid, (+,-)-Isomer;Abscisic Acid, (E,E)-(+-)-Isomer;Abscisic Acid, (E,Z)-(+,-)-Isomer;Abscisic Acid, (R)-Isomer;Abscisic Acid, (Z,E)-Isomer;Abscissic Acid;Abscissins

Chemical Property of Dormin

Chemical Property:

• Appearance/Colour: White to pale-yellow powder
• Vapor Pressure: 2.41E-10mmHg at 25°C
• Melting Point: 183-186 °C
• Boiling Point: 458.74 °C at 760 mmHg
• PKA: 4.87±0.33(Predicted)
• Flash Point: 245.36 °C
• PSA: 74.60000
• Density: 1.193 g/cm³
• LogP: 2.24990
• Storage Temp.: −20°C
• Sensitive.: Light Sensitive
• Solubility.: methanol: 50 mg/mL, may be clear to slightly hazy
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 264.13615911
• Heavy Atom Count: 19
• Complexity: 494

Purity/Quality:

90%,95%, ^*data from raw suppliers

Abscisic Acid ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=O)CC(C1(C=CC(=CC(=O)O)C)O)(C)C
• Isomeric SMILES: CC1=CC(=O)CC(C1(/C=C/C(=C\C(=O)O)/C)O)(C)C
• Recent ClinicalTrials: Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity
• Description: Abscisic Acid (ABA) is a phytohormone, a naturally occurring compound in plant. ABA is regarded as an inhibitor of plant growth and therefore usually used as a growth retardant in plant tissue culture. To date, ABA has been primarily used to promote the maturation of somatic embryos and the synthesis of storage reserves in embryos during maturation. ABA also acts as a controlling factor of germination and dormancy in somatic embryos and is generally used to induce somatic embryos into a quiescent state during plant tissue culture and synthetic seed studies. ABA stimulates the stomatal closure, thereby reducing transpirational water loss. Thus, it could be used as an anti-transpiration during the acclimatization of tissue culture-raised plants.
• Uses: abscission-accelerant; kinetin neucleotide synthesis inhibitor Abscisic acid (ABA) is an isoprenoid plant hormone (phytohormone) synthesized in all parts of plants and involved in many plant developmental processes. ABA is involved in establishing dormancy and regulation of stress responses. ABA inhibits fruit ripening, seed germination, photosynthesis and kinetin biosynthesis.

Technology Process of Dormin

There total 52 articles about Dormin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

abscisic acid 2-nitrobenzyl ester → 2-Nitrobenzyl alcohol (612-25-9) + Abscisic acid (2228-72-0,6755-41-5,7773-56-0,14375-45-2,14398-53-9,14674-85-2,40331-02-0,52392-36-6,72029-68-6,72029-69-7,113349-29-4,21293-29-8)

Guidance literature:

With water; at 30 ℃; for 168h; Sealed tube; Irradiation;

DOI:10.1016/j.phytol.2015.04.015

Reference yield:

4-O-sulpho-β-D-glucopyranosyl abscisate → D-glucose (50-99-7) + Abscisic acid (2228-72-0,6755-41-5,7773-56-0,14375-45-2,14398-53-9,14674-85-2,40331-02-0,52392-36-6,72029-68-6,72029-69-7,113349-29-4,21293-29-8)

Guidance literature:

With hydrogenchloride; In water; at 80 ℃; for 2h;

DOI:10.1080/14786419.2015.1126261

Reference yield:

(S)-methyl abscisate (6901-90-2,6901-96-8,14398-52-8,15734-36-8,15734-37-9,20496-94-0,30816-18-3,60102-39-8,79434-13-2,93164-18-2,132340-88-6,132488-74-5,7200-31-9) → methanol (67-56-1) + Abscisic acid (2228-72-0,6755-41-5,7773-56-0,14375-45-2,14398-53-9,14674-85-2,40331-02-0,52392-36-6,72029-68-6,72029-69-7,113349-29-4,21293-29-8)

Guidance literature:

With water; at 30 ℃; for 168h; Sealed tube; Irradiation;

DOI:10.1016/j.phytol.2015.04.015

upstream raw materials:

(S)-methyl abscisate

(2Z,4E)-5-<(S)-1-Hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl>-3-methylpenta-2,4-dienal

(2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-2,4-pentadienoic acid

methyl (2Z,4E)-5-((1S,4S)-1,4-dihydroxy-2,6,6-trimethylcyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid

Downstream raw materials:

(2Z,4E)-5-<(S)-1-Hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl>-3-methylpenta-2,4-dienal

methyl (1'S,2Z,4E,4'S)-5-(1,4-dihydroxy-2,6,6-trimethyl-2-cyclohexen-1-yl)-3-methyl-2,4-pentadien-1-ol

abscisic acid 1-(2-nitrophenyl)ethyl ester

(S)-methyl abscisate

Refernces

• 1、 Wan, Chuan,Zhang, Yuanzhi,Yang, Dongyan,Han, Xiaoqiang,Li, Xiuyun,Li, Hong,Xiao, Yumei,Qin, Zhaohai. "Synthesis and biological activity of abscisic acid esters". . p. 267 - 272. Retrieved 2015/06/22.
• 2、 Lim, Eng-Kiat,Doucet, Charlotte J.,Hou, Bingkai,Jackson, Rosamond G.,Abrams, Suzanne R.,Bowles, Dianna J.. "Resolution of (+)-abscisic acid using an Arabidopsis glycosyltransferase". . p. 143 - 147. Retrieved 2007/10/03.