(E)-amino[(2-chlorobenzyl)imino]methanaminium chloride

Base Information

• Chemical Name: (E)-amino[(2-chlorobenzyl)imino]methanaminium chloride
• CAS No.: 1128-91-2
• Molecular Formula: C8H10 Cl N3 . Cl H
• Molecular Weight: 220.101
• Mol file: 1128-91-2.mol

Synonyms:Guanidine,(o-chlorobenzyl)-, monohydrochloride (8CI); Guanidine,[(2-chlorophenyl)methyl]-, monohydrochloride (9CI)

Chemical Property of (E)-amino[(2-chlorobenzyl)imino]methanaminium chloride

Chemical Property:

• Vapor Pressure: 0.000144mmHg at 25°C
• Boiling Point: 332.6°C at 760 mmHg
• Flash Point: 154.9°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-amino[(2-chlorobenzyl)imino]methanaminium chloride

There total 3 articles about (E)-amino[(2-chlorobenzyl)imino]methanaminium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ N-(2-chlorobenzyl)guanidine hydrochloride (1128-91-2)

Guidance literature:

Reference yield: 82.0%

N-(2-chlorobenzyl)-2-amino-4,6-dimethoxypyrimidine → N-(2-chlorobenzyl)guanidine hydrochloride (1128-91-2)

Guidance literature:

With hydrogenchloride; In water; at 80 ℃; for 12h; Sealed tube; Green chemistry;

DOI:10.1016/j.tetlet.2015.07.007

Reference yield:

2-CHLOROBENZYLAMINE (89-97-4) → N-(2-chlorobenzyl)guanidine hydrochloride (1128-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / isopropyl alcohol / 12 h / 120 °C / Green chemistry

2: hydrogenchloride / water / 12 h / 80 °C / Sealed tube; Green chemistry

With hydrogenchloride; triethylamine; In water; isopropyl alcohol;

DOI:10.1016/j.tetlet.2015.07.007

upstream raw materials:

2-CHLOROBENZYLAMINE

Refernces

• 1、 -. "GUANIDINE COMPOUNDS AND USE THEREOF". Page/Page column 72; 81; 82. . Retrieved 2015/11/09.