Benzaldehyde phenylhydrazone

Base Information

• Chemical Name: Benzaldehyde phenylhydrazone
• CAS No.: 588-64-7
• Molecular Formula: C13H12N2
• Molecular Weight: 196.252
• Hs Code.: 2928009090
• European Community (EC) Number: 209-625-5
• NSC Number: 37088
• ChEMBL ID: CHEMBL1316039
• Mol file: 588-64-7.mol

Synonyms:Benzaldehyde phenylhydrazone;588-64-7;Benzalphenylhydrazine;1-benzylidene-2-phenylhydrazine;Benzaldehyde, phenylhydrazone;Diphenylhydrazone;N-[(Z)-(phenylmethylene)amino]aniline;Benzylidenephenylhydrazine;SCHEMBL42159;CHEMBL1316039;N-Phenyl-N'-benzylidenehydrazine;JGOAZQAXRONCCI-SDNWHVSQSA-N;NSC37088;MFCD00051318;NSC-37088;AKOS000281745;DS-9517;1-Phenyl-2-(phenylmethylidene)hydrazine;B0014;CS-0156495

Chemical Property of Benzaldehyde phenylhydrazone

Chemical Property:

• Vapor Pressure: 0.000201mmHg at 25°C
• Melting Point: 156°C
• Refractive Index: 1.567
• Boiling Point: 327.5 °C at 760 mmHg
• PKA: 13.65±0.10(Predicted)
• Flash Point: 151.9 °C
• PSA: 24.39000
• Density: 1.01g/cm³
• LogP: 3.20560
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 196.100048391
• Heavy Atom Count: 15
• Complexity: 189

Purity/Quality:

98% ^*data from raw suppliers

Benzaldehyde Phenylhydrazone >98.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=NNC2=CC=CC=C2
• Isomeric SMILES: C1=CC=C(C=C1)/C=N/NC2=CC=CC=C2

Technology Process of Benzaldehyde phenylhydrazone

There total 138 articles about Benzaldehyde phenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzaldehyde (100-52-7) + phenylhydrazine (100-63-0) → benzaldehyde phenylhydrazone (588-64-7)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane;

DOI:10.1039/c2ob25912e

Reference yield: 98.0%

phenylhydrazine hydrochloride (59-88-1) + benzaldehyde (100-52-7) → benzaldehyde phenylhydrazone (588-64-7)

Guidance literature:

With sodium acetate; In ethanol; at 80 ℃; for 0.0833333h; Microwave irradiation; air-cooling;

DOI:10.1021/co100015b

Reference yield: 98.0%

phenylhydrazine (100-63-0) + Benzaldoxime (932-90-1) → benzaldehyde phenylhydrazone (588-64-7)

Guidance literature:

iron(III) perchlorate; In 1,2-dichloro-ethane; at 20 ℃; for 12h;

DOI:10.1016/j.mencom.2007.05.021

upstream raw materials:

diazomethane

methyl magnesium iodide

diethyl ether

acetic acid-(benzylidene-phenyl-hydrazide)

Downstream raw materials:

(phenylazo)benzaldoxime

5-benzylidene-2-thiohydantoin

5-methyl-1,3-diphenyl-1H-pyrazole-4-carboxylic acid ethyl ester

ethyl 1,3,5-triphenyl-1H-pyrazole-4-carboxylate

Refernces

• 1、 -. "METHODS OF FORMING IMINES, IMINE-RELATED AND IMINE-DERIVED COMPOUNDS USING GREEN SOLVENTS". Paragraph 0186-0189. . Retrieved 2021/10/22.
• 2、 Zhang, Xin-Hui,Kang, Hui-Qin,Tao, Yuan-Yuan,Li, Yi-Han,Zhao, Jun-Ru,Ya-Gao,Ma, Li-Ying,Liu, Hong-Min. "Identification of novel 1,3-diaryl-1,2,4-triazole-capped histone deacetylase 6 inhibitors with potential anti-gastric cancer activity". . . Retrieved 2021/04/12.