Mast cell degranulating peptide (vespula lewisii), 3-L-tryptophan-5-glycine-6-L-isoleucine-9-L-methionine-13-L-leucine-

Base Information

• Chemical Name: Mast cell degranulating peptide (vespula lewisii), 3-L-tryptophan-5-glycine-6-L-isoleucine-9-L-methionine-13-L-leucine-
• CAS No.: 72093-22-2
• Molecular Formula: C₇₃H₁₂₆N₂₀O₁₅S
• Molecular Weight: 1555.99
• Mol file: 72093-22-2.mol

Synonyms:SCHEMBL16197370;Mast cell degranulating peptide (vespula lewisii), 3-L-tryptophan-5-glycine-6-L-isoleucine-9-L-methionine-13-L-leucine-

Chemical Property of Mast cell degranulating peptide (vespula lewisii), 3-L-tryptophan-5-glycine-6-L-isoleucine-9-L-methionine-13-L-leucine-

Chemical Property:

• Appearance/Colour: White lyophilised solid
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.558
• Boiling Point: 1797.4 °C at 760 mmHg
• Flash Point: 1040.8 °C
• PSA: 609.65000
• Density: 1.207 g/cm³
• LogP: 6.99990
• Storage Temp.: -15°C
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 20
• Hydrogen Bond Acceptor Count: 20
• Rotatable Bond Count: 54
• Exact Mass: 1554.94322457
• Heavy Atom Count: 109
• Complexity: 2970

Purity/Quality:

98%Min ^*data from raw suppliers

Mastoparan X ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)C(C(=O)NC(CC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)N)N
• Isomeric SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NC([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N)N
• Uses: Has effects similar to mastoparan; binds with high affinity to calmodulin and inhibits sarcoplasmic reticulum calcium-ATPase

Technology Process of Mast cell degranulating peptide (vespula lewisii), 3-L-tryptophan-5-glycine-6-L-isoleucine-9-L-methionine-13-L-leucine-

There total 1 articles about Mast cell degranulating peptide (vespula lewisii), 3-L-tryptophan-5-glycine-6-L-isoleucine-9-L-methionine-13-L-leucine- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Z(OMe)-Ile-Asn-Trp-Lys(Z)-Gly-Ile-Ala-Ala-Met(O)-Ala-Lys(Z)-Lys(Z)-Leu-Leu-NH2 (74105-17-2) → Mastoparan X (72093-22-2)

Guidance literature:

With mercaptoethyl alcohol; methanesulfonic acid; 3-methyl-phenol; Yield given. Multistep reaction; 1.) 0 deg C, 30 min, room temp., 60 min, 2.) H₂O, 70 deg C, 20 h;

DOI:10.1248/cpb.28.882

upstream raw materials:

Z(OMe)-Ile-Asn-Trp-Lys(Z)-Gly-Ile-Ala-Ala-Met(O)-Ala-Lys(Z)-Lys(Z)-Leu-Leu-NH₂

Refernces