(S)-lipoic acid

Base Information Edit

Chemical Name:(S)-lipoic acid
CAS No.:1077-27-6
Deprecated CAS:127254-35-7
Molecular Formula:C₈H₁₄O₂S₂
Molecular Weight:206.33
Hs Code.:
European Community (EC) Number:664-251-3
UNII:J2Y905FQ57
DSSTox Substance ID:DTXSID40904735
Nikkaji Number:J231.967E
Wikipedia:Lipoic_acid
Wikidata:Q21097956
Metabolomics Workbench ID:52348
ChEMBL ID:CHEMBL1234071
Mol file:1077-27-6.mol

Synonyms:Acid, alpha-Lipoic;Alpha Lipogamma;alpha Lipoic Acid;Alpha Lipon Stada;alpha Liponaure Heumann;Alpha Liponsaure Sofotec;alpha Liponsaure von ct;Alpha Lippon AL;alpha Vibolex;Alpha-Lipogamma;alpha-Lipoic Acid;Alpha-Lipon Stada;alpha-Liponaure Heumann;Alpha-Liponsaure Sofotec;alpha-Liponsaure von ct;Alpha-Lippon AL;alpha-Vibolex;Alphaflam;AlphaLipogamma;AlphaLipon Stada;alphaLiponaure Heumann;AlphaLiponsaure Sofotec;alphaLiponsaure von ct;AlphaLippon AL;alphaVibolex;Azulipont;biomo lipon;biomo-lipon;biomolipon;duralipon;espa lipon;espa-lipon;espalipon;Fenint;Injekt, Thiogamma;Juthiac;Lipoic Acid;Liponsaure ratiopharm;Liponsaure-ratiopharm;Liponsaureratiopharm;MTW Alphaliponsaure;MTW-Alphaliponsaure;MTWAlphaliponsaure;Neurium;Pleomix Alpha;Pleomix Alpha N;Pleomix-Alpha;Pleomix-Alpha N;PleomixAlpha;PleomixAlpha N;Thioctacid;Thioctacide T;Thioctic Acid;Thiogamma Injekt;Thiogamma oral;Tromlipon;Verla Lipon;Verla-Lipon;VerlaLipon

Suppliers and Price of (S)-lipoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-(?)-α -Lipoic acid
25mg
$ 185.00

TRC
(S)-(?)-α -Lipoic acid
5mg
$ 95.00

Sigma-Aldrich
(S)-(?)-α -Lipoic acid ≥97% (HPLC)
10mg
$ 59.90

Sigma-Aldrich
(S)-(?)-α -Lipoic acid ≥97% (HPLC)
100mg
$ 451.00

Sigma-Aldrich
(S)-(?)-α -Lipoic acid ≥97% (HPLC)
500mg
$ 1080.00

Medical Isotopes, Inc.
(S)-(?)-α -Lipoic acid
10 mg
$ 5750.00

Crysdot
(S)-5-(1,2-Dithiolan-3-yl)pentanoicacid 97%
10g
$ 446.00

Chemenu
(S)-5-(1,2-Dithiolan-3-yl)pentanoicacid 97%
250mg
$ 655.00

American Custom Chemicals Corporation
S(-)-ALPHA-LIPOIC ACID 95.00%
10MG
$ 6063.75

Ambeed
(S)-5-(1,2-Dithiolan-3-yl)pentanoicacid 98%
100g
$ 348.00

Total 31 raw suppliers

Chemical Property of (S)-lipoic acid Edit

Chemical Property:

Vapor Pressure:3.07E-06mmHg at 25°C
Melting Point:47 °C
Refractive Index:-114 ° (C=1, EtOH)
Boiling Point:362.5 °C at 760 mmHg
PKA:4.75±0.10(Predicted)
Flash Point:173 °C
PSA：87.90000
Density:1.218g/cm³
LogP:2.78510
Storage Temp.:?20°C
Solubility.:Chloroform (Slightly, Heated), Methanol (Slightly)
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:206.04352203
Heavy Atom Count:12
Complexity:150

Purity/Quality:

99% ^*data from raw suppliers

(S)-(?)-α -Lipoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CSSC1CCCCC(=O)O
Isomeric SMILES:C1CSS[C@H]1CCCCC(=O)O
Recent ClinicalTrials:Lipoic Acid for Progressive Multiple Sclerosis (MS)
Uses A fat-metabolism stimulator A fat-metabolism stimulator. Antioxidant.

Technology Process of (S)-lipoic acid

There total 49 articles about (S)-lipoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%