Eleutheroside E

Base Information

• Chemical Name: Eleutheroside E
• CAS No.: 39432-56-9
• Molecular Formula: C₃₄H₄₆O₁₈
• Molecular Weight: 742.728
• Hs Code.: 29389090
• Mol file: 39432-56-9.mol

Synonyms:b-D-Glucopyranoside,(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis(2,6-dimethoxy-4,1-phenylene)bis-, [1R-(1a,3ab,4b,6aa)]-;(2R,3S,4R,5R,6S)-2-[4-[4-[3,5-Dimethoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[4,3-c]furan-1-yl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol;

Chemical Property of Eleutheroside E

Chemical Property:

• Appearance/Colour: colourless microcrystalline powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 255 - 260oC
• Refractive Index: 1.615
• Boiling Point: 935.7 °C at 760 mmHg
• PKA: 12.45±0.70(Predicted)
• Flash Point: 519.7 °C
• PSA: 254.14000
• Density: 1.474 g/cm³
• LogP: -1.84640
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Ethyl Acetate (Slightly), Pyridine (Slightly, Sonicated)

Purity/Quality:

100% Natural & No pollution ^*data from raw suppliers

Eleutheroside E ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Eleutheroside E is used in the treatment of collagen-induced arthritis. Used in the suppression of inflammatory cytokine release. Successful in the treatment of rheumatoid arthritis. Also used in the regulation of adipogenesis

Technology Process of Eleutheroside E

There total 3 articles about Eleutheroside E which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C50H62O26 (6746-69-6,66007-45-2,66791-78-4,104758-17-0) → (+/-)-Singaresinol-4',4'-O-bis-β-D-glucoside (573-44-4,6216-79-1,39432-56-9,66791-77-3,79484-75-6,96038-87-8,100569-79-7)

Guidance literature:

With sodium methylate; In methanol; Yield given; pH 10;

DOI:10.1016/S0031-9422(00)98258-X

Reference yield:

trans-sinapyl alcohol (20675-96-1) → (+/-)-Singaresinol-4',4'-O-bis-β-D-glucoside (573-44-4,6216-79-1,39432-56-9,66791-77-3,79484-75-6,96038-87-8,100569-79-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 67 percent / CuSO₄, air / H₂O / 48 h / 25 °C / Irradiation

2: 2.5 percent KOH / acetone / 48 h

3: 1 M NaOMe / methanol / pH 10

With potassium hydroxide; air; sodium methylate; copper(II) sulfate; In methanol; water; acetone;

DOI:10.1016/S0031-9422(00)98258-X

Reference yield:

(+/-)-syringaresinol (487-35-4,551-29-1,1177-14-6,6216-81-5,6216-82-6,19046-36-7,21453-69-0,21453-71-4,51152-20-6,51197-10-5,72258-43-6) → (+/-)-Singaresinol-4',4'-O-bis-β-D-glucoside (573-44-4,6216-79-1,39432-56-9,66791-77-3,79484-75-6,96038-87-8,100569-79-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.5 percent KOH / acetone / 48 h

2: 1 M NaOMe / methanol / pH 10

With potassium hydroxide; sodium methylate; In methanol; acetone;

DOI:10.1016/S0031-9422(00)98258-X

upstream raw materials:

C₅₀H₆₂O₂₆

trans-sinapyl alcohol

(+/-)-syringaresinol

Downstream raw materials:

(-)-Syringaresinol

(+)-dia-syringaresinol

C₅₀H₆₂O₂₆

Refernces