8-hydroxy-3,6-dioxaoctanal

Base Information

• Chemical Name: 8-hydroxy-3,6-dioxaoctanal
• CAS No.: 108306-81-6
• Molecular Formula: C₆H₁₂O₄
• Molecular Weight: 148.159
• Hs Code.: 2912499000
• Mol file: 108306-81-6.mol

Synonyms:Acetaldehyde,[2-(2-hydroxyethoxy)ethoxy]- (9CI)

Chemical Property of 8-hydroxy-3,6-dioxaoctanal

Chemical Property:

• Vapor Pressure: 0.00569mmHg at 25°C
• Boiling Point: 242.7°Cat760mmHg
• Flash Point: 97.1°C
• PSA: 55.76000
• Density: 1.096g/cm³
• LogP: -0.78920

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-hydroxy-3,6-dioxaoctanal

There total 2 articles about 8-hydroxy-3,6-dioxaoctanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → 8-hydroxy-3,6-dioxaoctanal (108306-81-6)

Guidance literature:

With benzophenone; bis(cyclopentadienyl)dihydrozirconium; at 170 ℃; for 10h;

DOI:10.1055/s-1986-31775

Reference yield:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → 1,2-bis-(2-oxo-ethoxy)-ethane (89489-75-8) + 8-hydroxy-3,6-dioxaoctanal (108306-81-6)

Guidance literature:

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; nitromethane; oxygen; 1,10-ethyleneisoalloxazinium chloride; at 40 ℃; for 24h;

DOI:10.1021/acs.joc.0c01013

upstream raw materials:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

Refernces

• 1、 Nakano, Tatsuya,Terada, Takanobu,Ishii, Yasutaka,Ogawa, Masaya. "Chemoselective Oxidation of the Primary Alcohol Function of Diols Catalyzed by Zirconocene Complexes". . p. 774 - 776. Retrieved 2007/10/02.