D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,4-bis(dihydrogen phosphate)

Base Information

• Chemical Name: D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,4-bis(dihydrogen phosphate)
• CAS No.: 165883-85-2
• Molecular Formula: C₄₁H₈₁O₁₉P₃
• Molecular Weight: 971.004
• Mol file: 165883-85-2.mol

Synonyms:D-myo-Inositol,1-[2,3-bis[(1-oxohexadecyl)oxy]propyl hydrogen phosphate] 3,4-bis(dihydrogenphosphate), (R)-

Chemical Property of D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,4-bis(dihydrogen phosphate)

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 995.9°C at 760 mmHg
• Flash Point: 556.1°C
• PSA: 332.00000
• Density: 1.27g/cm³
• LogP: 7.95830

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,4-bis(dihydrogen phosphate)

There total 6 articles about D-myo-Inositol, 1-(2R)-2,3-bis(1-oxohexadecyl)oxypropyl hydrogen phosphate 3,4-bis(dihydrogen phosphate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Hexadecanoic acid (R)-2-{benzyloxy-[(1S,2R,3R,4S,5S,6S)-2,3,6-tris-benzyloxy-4,5-bis-(bis-benzyloxy-phosphoryloxy)-cyclohexyloxy]-phosphoryloxy}-1-hexadecanoyloxymethyl-ethyl ester (180979-81-1) → 1D-1-(1',2'-di-O-hexadecanoyl-sn-glycero(3')phospho)-myo-inositol 3,4-bis(ohosphate) (165883-85-2)

Guidance literature:

With hydrogen; palladium dihydroxide; In tert-butyl alcohol; at 30 ℃; for 48h; under 2585.74 Torr;

Reference yield: 91.0%

1D-O-(1,2-di-O-palmitoyl-sn-glycerol-3-O-methylphospho)-2,5,6-O-tris(methoxymethylene)-myo-inositol 3,4-bis(dibenzyl phosphate) (496808-58-3) → 1D-1-(1',2'-di-O-hexadecanoyl-sn-glycero(3')phospho)-myo-inositol 3,4-bis(ohosphate) (165883-85-2)

Guidance literature:

1D-O-(1,2-di-O-palmitoyl-sn-glycerol-3-O-methylphospho)-2,5,6-O-tris(methoxymethylene)-myo-inositol 3,4-bis(dibenzyl phosphate); With trimethylamine; at 20 ℃; for 36h;

With hydrogen; palladium on activated charcoal; In methanol; for 5h; atmospheric pressure;

With boron trifluoride diethyl etherate; ethanethiol; for 1h; Further stages.;

DOI:10.1021/jo0206418

Reference yield:

Hexadecanoic acid (S)-2-{benzyloxy-[(1R,2S,3S,4R,5R,6R)-2,3,6-tris-benzyloxy-4,5-bis-(bis-benzyloxy-phosphoryloxy)-cyclohexyloxy]-phosphoryloxy}-1-hexadecanoyloxymethyl-ethyl ester → 1D-3-(2',3'-di-O-hexadecanoyl-sn-glycero(1')phospho)-myo-inositol 1,6-bis(ohosphate) (165883-85-2)

Guidance literature:

With hydrogen; palladium dihydroxide; In tert-butyl alcohol; under 3102.9 Torr;

DOI:10.1039/a703045b

upstream raw materials:

Hexadecanoic acid (S)-2-{benzyloxy-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris-benzyloxy-4,5-bis-(bis-benzyloxy-phosphoryloxy)-cyclohexyloxy]-phosphoryloxy}-1-hexadecanoyloxymethyl-ethyl ester

Hexadecanoic acid (R)-2-{benzyloxy-[(1S,2R,3R,4S,5S,6S)-2,3,6-tris-benzyloxy-4,5-bis-(bis-benzyloxy-phosphoryloxy)-cyclohexyloxy]-phosphoryloxy}-1-hexadecanoyloxymethyl-ethyl ester

1D-O-(1,2-di-O-palmitoyl-sn-glycerol-3-O-methylphospho)-2,5,6-O-tris(methoxymethylene)-myo-inositol 3,4-bis(dibenzyl phosphate)

Refernces

• 1、 Kubiak, Robert J.,Bruzik, Karol S.. "Comprehensive and uniform synthesis of all naturally occurring phosphorylated phosphatidylinositols". . p. 960 - 968. Retrieved 2007/10/03.
• 2、 Painter, Gavin F.,Grove, Simon J. A.,Gilbert, Lan H.,Holmes, Andrew B.,Raithby, Paul R.,Hill, Malcolm L.,Hawking, Phillip T.,Stephens, Leonard R.. "General synthesis of 3-phosphorylated mj'o-inositol phospholipids and derivatives". . p. 923 - 935. Retrieved 2007/10/03.