3-Methoxy-2,2-dimethyloxirane

Base Information

• Chemical Name: 3-Methoxy-2,2-dimethyloxirane
• CAS No.: 26196-04-3
• Molecular Formula: C₅H₁₀O₂
• Molecular Weight: 102.133
• European Community (EC) Number: 247-514-3
• NSC Number: 176994
• UNII: 1Y8YXB766W
• DSSTox Substance ID: DTXSID601031044
• Nikkaji Number: J208.752I
• Wikidata: Q27253178
• Mol file: 26196-04-3.mol

Synonyms:26196-04-3;3-Methoxy-2,2-dimethyloxirane;1-Methoxy-2-methylpropylene Oxide;2,2-Dimethyl-1-methoxyethylene oxide;Oxirane, 3-methoxy-2,2-dimethyl-;CCRIS 3761;EINECS 247-514-3;1,2-Epoxy-1-methoxy-2-methylpropane;BRN 0102777;UNII-1Y8YXB766W;Propane, 1,2-epoxy-1-methoxy-2-methyl-;1Y8YXB766W;2,2-Dimethyl-3-methoxyoxirane;NSC-176994;4-17-00-01035 (Beilstein Handbook Reference);Oxirane,3-methoxy-2,2-dimethyl-;NSC176994;O(C)C1OC1(C)C;SCHEMBL1122798;3-methoxy-2,2-dimethyl-oxirane;DTXSID601031044;MFCD00010676;AKOS015852070;NSC 176994;.+/-.-1-Methoxy-2-methylpropylene oxide;LS-120799;FT-0608004;Q27253178

Chemical Property of 3-Methoxy-2,2-dimethyloxirane

Chemical Property:

• Vapor Pressure: 56.1mmHg at 25°C
• Melting Point: 96-98 °C
• Refractive Index: 1.416
• Boiling Point: 93.5 °C at 760 mmHg
• Flash Point: 6°C
• PSA: 21.76000
• Density: 0.96 g/cm³
• LogP: 0.76770
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 102.068079557
• Heavy Atom Count: 7
• Complexity: 78.1

Purity/Quality:

99% ^*data from raw suppliers

1-METHOXY-2-METHYLPROPYLENE OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xi
• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-33-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(C(O1)OC)C

Technology Process of 3-Methoxy-2,2-dimethyloxirane

There total 4 articles about 3-Methoxy-2,2-dimethyloxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-methoxy-2-methylprop-1-ene (17574-84-4) → 1-methoxy-2-methylpropylene oxide (26196-04-3,137688-22-3,137688-23-4)

Guidance literature:

With oxygen; In acetonitrile; at 60 ℃; for 14h; under 760.051 Torr; Catalytic behavior;

DOI:10.1007/s11164-017-3027-z

Reference yield:

2-chloroisobutyraldehyde (917-93-1) + sodium methylate (124-41-4) → 1-methoxy-2-methylpropylene oxide (26196-04-3,137688-22-3,137688-23-4)

Guidance literature:

DOI:10.1021/ja01570a036

Reference yield:

3,6,9-trioxaundecane (112-36-7) + 2-chloroisobutyraldehyde (917-93-1) + sodium methylate (124-41-4) → 1-methoxy-2-methylpropylene oxide (26196-04-3,137688-22-3,137688-23-4)

Guidance literature:

DOI:10.1021/ja01570a036

upstream raw materials:

3,6,9-trioxaundecane

2-chloroisobutyraldehyde

sodium methylate

1-methoxy-2-methylprop-1-ene

Downstream raw materials:

1-Methoxy-2-methylpropane-1,2-diol 1-acetate

1-Methoxy-2-methylpropan-2-ol

3-(4-toluenesulfonyl)-4,4-dimethyl-5-methoxy-2-oxazolidone

Refernces

• 1、 Kazemnejadi, Milad,Mahmoudi, Boshra,Sharafi, Zeinab,Nasseri, Mohammad Ali,Allahresani, Ali,Esmaeilpour, Mohsen. "Synthesis and characterization of a new poly α-amino acid Co(II)-complex supported on magnetite graphene oxide as an efficient heterogeneous magnetically recyclable catalyst for efficient free-coreductant gram-scale epoxidation of olefins with molecular oxygen". . p. 59 - 69. Retrieved 2019/06/13.
• 2、 Kazemnejadi, Milad,Shakeri, Alireza,Nikookar, Mahsa,Mohammadi, Mohammad,Esmaeilpour, Mohsen. "Co(II) Schiff base complex decorated on polysalicylaldehyde as an efficient, selective, heterogeneous and reusable catalyst for epoxidation of olefins in mild and self-coreductant conditions". . p. 6889 - 6910. Retrieved 2017/10/05.