Spirolaxin

Base Information

• Chemical Name: Spirolaxin
• CAS No.: 126382-01-2
• Molecular Formula: C₂₃H₃₂O₆
• Molecular Weight: 404.503
• Mol file: 126382-01-2.mol

Synonyms:1(3H)-Isobenzofuranone,5-hydroxy-7-methoxy-3-[5-[(2R,5R,7R)-2-methyl-1,6-dioxaspiro[4.5]dec-7-yl]pentyl]-(9CI); 1,6-Dioxaspiro[4.5]decane, 1(3H)-isobenzofuranone deriv.;(+)-Spirolaxine; Spirolaxin; Spirolaxine

Chemical Property of Spirolaxin

Chemical Property:

• PSA: 74.22000
• LogP: 5.02710

Purity/Quality:

98% ^*data from raw suppliers

Spirolaxine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Spirolaxine is a long-chain phthalide produced by the fungus S. laxum that has antibacterial properties. Spirolaxine is a potent anti-H. pylori agent (MIC = 0.2 μg/cm3) with weak activity against E. coli. Spirolaxine (1-40 μM) inhibits proliferation of endothelial (BMEC, HUVEC) and tumor (LoVo, HL-60) cells in culture. B. megaterium and C. echinulate produce hydroxylated metabolites of spirolaxine when given spirolaxine as a substrate.
• Uses: Spirolaxine is a bioactive undecaketide fungal metabolite found in Sporotrichum laxum ATCC 15155. Spirolaxine exhibits anti-Helicobacter pylori property.