2,3-Dimethylpyridine

Base Information

• Chemical Name: 2,3-Dimethylpyridine
• CAS No.: 583-61-9
• Molecular Formula: C7H9N
• Molecular Weight: 107.155
• Hs Code.: H9N MOL WT. 107.16
• European Community (EC) Number: 248-287-3,209-514-1
• NSC Number: 2157
• UNII: 5Q0F649H6G
• DSSTox Substance ID: DTXSID6060395
• Nikkaji Number: J7.444F
• Wikidata: Q27262718
• ChEMBL ID: CHEMBL3303914
• Mol file: 583-61-9.mol

Synonyms:2,3-Lutidine;2,3-DIMETHYLPYRIDINE;583-61-9;DIMETHYLPYRIDINE;Pyridine, 2,3-dimethyl-;Pyridine, dimethyl-;2,3-dimethyl-pyridine;2,3-Dimethylpyridine-d9;27175-64-0;UNII-5Q0F649H6G;5Q0F649H6G;NSC 2157;NSC-2157;EINECS 209-514-1;EINECS 248-287-3;AI3-24280;350818-65-4;2-3-Lutidine;MFCD00009605;Pyridine,3-dimethyl-;2,3-d1methylpyridine;2,3-Lutidine, 99%;SCHEMBL65397;CHEMBL3303914;DTXSID6060395;NSC2157;BCP26360;AKOS009028879;CS-W011290;BP-21057;CS-17343;FT-0609747;FT-0693465;L0063;EN300-19111;P19755;A831849;W-105397;2,3,4-trideuterio-5,6-bis(trideuteriomethyl)pyridine;Q27262718;2,3-Dimethylpyridine;Dimethylpyridine

Chemical Property of 2,3-Dimethylpyridine

Chemical Property:

• Appearance/Colour: clear colorless to slightly yellow liquid
• Vapor Pressure: 2.01E-12mmHg at 25°C
• Melting Point: -15 °C(lit.)
• Refractive Index: n20/D 1.508(lit.)
• Boiling Point: 160.7 °C at 760 mmHg
• PKA: 6.57(at 25℃)
• Flash Point: 45.4 °C
• PSA: 12.89000
• Density: 0.93 g/cm³
• LogP: 1.69840
• Storage Temp.: Flammables area
• Water Solubility.: 95 g/L (26 ºC)
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 107.073499291
• Heavy Atom Count: 8
• Complexity: 70.8

Purity/Quality:

99% ^*data from raw suppliers

2,3-Lutidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn, F, Xi
• Hazard Codes: Xn,F,Xi
• Statements: 10-22-37/38-41-20/21/22-36/37/38
• Safety Statements: 16-26-39-36/37-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Pyridines
• Canonical SMILES: CC1=C(N=CC=C1)C
• Uses: 2,3-Lutidine is a lansoprazole intermediates. It is used as pharmaceutical intermediate.

Technology Process of 2,3-Dimethylpyridine

There total 42 articles about 2,3-Dimethylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.2%

2-Methyl-3-acetoxymethylpyridin (87851-05-6) → 2,3-Lutidine (583-61-9)

Guidance literature:

With hydrogen; Pd-BaSO₄; In ethanol; for 0.5h; Ambient temperature;

DOI:10.1002/ardp.19833161014

Reference yield: 81.0%

N-(3-methyl-2-methyl-2H-pyridin-1-yl)-N-methyl-benzamidine (777944-43-1) → 2,3-Lutidine (583-61-9)

Guidance literature:

N-(3-methyl-2-methyl-2H-pyridin-1-yl)-N-methyl-benzamidine; With manganese triacetate; acetic acid; at 60 ℃; for 2h;

With water; acetic acid; at 80 ℃;

DOI:10.1021/ol048624n

Reference yield: 80.0%

5-chloro-5,6-dimethyl-2,3,4,5-tetrahydropyridine (326893-28-1) → 2,3-Lutidine (583-61-9)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; Heating;

DOI:10.1021/jo000724t

upstream raw materials:

5,6-dimethyl-1,2,3,4-tetrahydro-pyridine

6-chloro-2,3-dimethylpyridine

1-Methyl-3-acetylpiperidine

4,6-dichloro-2,3-dimethyl-pyridine

Downstream raw materials:

2-(2-hydroxyethyl)-3-methylpyridine

o-tolyl isocyanide

3-methyl-2-(4-nitro-trans-styryl)-pyridine

3-methyl-2-[(E)-2-phenylethenyl]pyridine

Refernces

• 1、 -. "Promiscuous G-protein compositions and their use". . . Retrieved 2008/06/13.
• 2、 -. "Inhibitors of cell proliferation, angiogenesis, fertility, and muscle contraction". . . Retrieved 2008/06/13.