32-oxolanosterol

Base Information

• Chemical Name: 32-oxolanosterol
• CAS No.: 79294-83-0
• Molecular Formula: C₃₀H₄₈O₂
• Molecular Weight: 440.71
• Mol file: 79294-83-0.mol

Synonyms:32-oxolanosterol

Chemical Property of 32-oxolanosterol

Chemical Property:

• Vapor Pressure: 3.42E-13mmHg at 25°C
• Boiling Point: 524.5°C at 760 mmHg
• Flash Point: 221.5°C
• PSA: 37.30000
• Density: 1.02g/cm³
• LogP: 7.65810

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 32-oxolanosterol

There total 4 articles about 32-oxolanosterol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetic acid (3S,10S,13R,14S)-17-((R)-1,5-dimethyl-hex-4-enyl)-14-formyl-4,4,10,13-tetramethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (119273-04-0) → (3S,10S,13R,14S)-17-((R)-1,5-Dimethyl-hex-4-enyl)-3-hydroxy-4,4,10,13-tetramethyl-1,2,3,4,5,6,7,10,11,12,13,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-14-carbaldehyde (79294-83-0)

Guidance literature:

With potassium carbonate; In methanol; Yield given;

DOI:10.1021/ja00188a059

Reference yield:

(3S,10S,13R,14S)-17-((R)-1,5-Dimethyl-hex-4-enyl)-4,4,10,13-tetramethyl-14-vinyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol (119272-96-7) → (3S,10S,13R,14S)-17-((R)-1,5-Dimethyl-hex-4-enyl)-3-hydroxy-4,4,10,13-tetramethyl-1,2,3,4,5,6,7,10,11,12,13,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-14-carbaldehyde (79294-83-0)

Guidance literature:

Multi-step reaction with 4 steps

2: 93 percent / m-CPBA / CH₂Cl₂ / 23 °C

3: 1.) O₃, 2.) Zn, AcOH, NaI / 1.) CH₂Cl₂, MeOH, -78 deg C, 2.) -78 deg C, 1 h; 40 deg C, 6 h

4: K₂CO₃ / methanol

With potassium carbonate; ozone; acetic acid; 3-chloro-benzenecarboperoxoic acid; sodium iodide; zinc; In methanol; dichloromethane;

DOI:10.1021/ja00188a059

Reference yield:

Acetic acid (3S,10S,13R,14S)-17-((R)-1,5-dimethyl-hex-4-enyl)-4,4,10,13-tetramethyl-14-vinyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (119273-02-8) → (3S,10S,13R,14S)-17-((R)-1,5-Dimethyl-hex-4-enyl)-3-hydroxy-4,4,10,13-tetramethyl-1,2,3,4,5,6,7,10,11,12,13,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-14-carbaldehyde (79294-83-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / m-CPBA / CH₂Cl₂ / 23 °C

2: 1.) O₃, 2.) Zn, AcOH, NaI / 1.) CH₂Cl₂, MeOH, -78 deg C, 2.) -78 deg C, 1 h; 40 deg C, 6 h

3: K₂CO₃ / methanol

With potassium carbonate; ozone; acetic acid; 3-chloro-benzenecarboperoxoic acid; sodium iodide; zinc; In methanol; dichloromethane;

DOI:10.1021/ja00188a059

upstream raw materials:

Acetic acid (3S,10S,13R,14S)-17-((R)-1,5-dimethyl-hex-4-enyl)-14-formyl-4,4,10,13-tetramethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

(3S,10S,13R,14S)-17-((R)-1,5-Dimethyl-hex-4-enyl)-4,4,10,13-tetramethyl-14-vinyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

Acetic acid (3S,10S,13R,14S)-17-((R)-1,5-dimethyl-hex-4-enyl)-4,4,10,13-tetramethyl-14-vinyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Acetic acid (3S,10S,13R,14S)-17-[(R)-3-(3,3-dimethyl-oxiranyl)-1-methyl-propyl]-4,4,10,13-tetramethyl-14-vinyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Downstream raw materials:

(3S,10S,13R,14S)-17-((R)-1,5-Dimethyl-hex-4-enyl)-14-hydroxymethyl-4,4,10,13-tetramethyl-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

Refernces