Aminoacetonitrile hydrochloride

Base Information

• Chemical Name: Aminoacetonitrile hydrochloride
• CAS No.: 6011-14-9
• Deprecated CAS: 2361025-46-7
• Molecular Formula: C2H5ClN2
• Molecular Weight: 92.5281
• Hs Code.: 29269090
• Mol file: 6011-14-9.mol

Synonyms:Acetonitrile,amino-, monohydrochloride (9CI);Glycinonitrile, monohydrochloride (8CI);2-Aminoacetonitrile hydrochloride;Aminoacetonitrile monohydrochloride;Glycinonitrile hydrochloride;a-Aminoacetonitrilehydrochloride;

Chemical Property of Aminoacetonitrile hydrochloride

Chemical Property:

• Appearance/Colour: White to off-white crystalline powder
• Vapor Pressure: 1.99mmHg at 25°C
• Melting Point: 172-174 °C
• Boiling Point: 164.2 °C at 760 mmHg
• Flash Point: 53.1 °C
• PSA: 49.81000
• LogP: 0.97098
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Solubility.: Methanol (Slightly, Heated), Water
• Water Solubility.: Soluble in water 20°C, 1000g/L.
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 92.0141259
• Heavy Atom Count: 5
• Complexity: 39.2

Purity/Quality:

99% ^*data from raw suppliers

AminoacetonitrileHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R22:Harmful if swallowed.; R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R22:Harmful if swallowed.; R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: 20/21/22-36/37/38-25
• Safety Statements: 22-36/37-45-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C#N)[NH3+].[Cl-]
• Uses: Used as pharmaceutical intermediates, organic synthetic raw material transportation.

Technology Process of Aminoacetonitrile hydrochloride

There total 5 articles about Aminoacetonitrile hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.8%

2-aminoacetonitrile (540-61-4) → 2-aminoacetonitrile hydrochloride (6011-14-9)

Guidance literature:

With hydrogenchloride; at 20 - 30 ℃; for 2h; Temperature;

Reference yield:

sodium cyanide (773837-37-9) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → 2-aminoacetonitrile hydrochloride (6011-14-9)

Guidance literature:

sodium cyanide; formaldehyd; With ammonium hydroxide;

With hydrogenchloride;

DOI:10.1039/c7cc02801f

Reference yield:

→ N-cyanomethyl-3-fluoro-4-(4-fluoro-benzyloxy)-benzamide (636794-39-3) + 2-aminoacetonitrile hydrochloride (6011-14-9)

Guidance literature:

upstream raw materials:

sodium cyanide

formaldehyd

2-aminoacetonitrile

Downstream raw materials:

2-phthalimidoacetamide

pyrazin-2(1H)-one

p-tolylaminoacetonitrile

N-phenylglycinonitrile

Refernces

• 1、 -. "Method for synthesizing aminoacetonitrile hydrochloride from hydrocyanic acid". Page/Page column 0031; 0035; 0039; 0043; 0047; 0051; 0055; 0059. . Retrieved 2020/08/18.