Technology Process of [2-(2,6-Dichloro-3-methoxyanilino)phenyl]acetic acid
There total 4 articles about [2-(2,6-Dichloro-3-methoxyanilino)phenyl]acetic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium methylate; hydrazine hydrate;
In
2-methoxy-ethanol;
Yield given;
1.) from 60 deg C to 150 deg C, 2.) 150 deg C, 1 h;
DOI:10.1021/jm00171a008
- Guidance literature:
-
Multi-step reaction with 4 steps
1: benzene / 2 h / Ambient temperature
2: AlCl3 / various solvent(s) / 20 h / Ambient temperature
3: 1 N NaOH / ethanol; H2O / 0.17 h / Heating
4: hydrazine hydrate, NaOCH3 / 2-methoxy-ethanol / 1.) from 60 deg C to 150 deg C, 2.) 150 deg C, 1 h
With
sodium hydroxide; aluminium trichloride; sodium methylate; hydrazine hydrate;
In
ethanol; 2-methoxy-ethanol; water; benzene;
DOI:10.1021/jm00171a008
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1 N NaOH / ethanol; H2O / 0.17 h / Heating
2: hydrazine hydrate, NaOCH3 / 2-methoxy-ethanol / 1.) from 60 deg C to 150 deg C, 2.) 150 deg C, 1 h
With
sodium hydroxide; sodium methylate; hydrazine hydrate;
In
ethanol; 2-methoxy-ethanol; water;
DOI:10.1021/jm00171a008