Tetrahydrofurfuryl salicylate

Base Information

• Chemical Name: Tetrahydrofurfuryl salicylate
• CAS No.: 2217-35-8
• Molecular Formula: C12H14O4
• Molecular Weight: 222.241
• Hs Code.: 2932190090
• European Community (EC) Number: 218-711-1
• NSC Number: 68484
• UNII: 4KUH7HZ54V
• DSSTox Substance ID: DTXSID501043224
• Nikkaji Number: J299.174H
• Wikidata: Q27259924
• Mol file: 2217-35-8.mol

Synonyms:Tetrahydrofurfuryl salicylate;2217-35-8;Thurfyl salicylate;(Tetrahydrofuran-2-yl)methyl 2-hydroxybenzoate;oxolan-2-ylmethyl 2-hydroxybenzoate;UNII-4KUH7HZ54V;4KUH7HZ54V;EINECS 218-711-1;NSC-68484;Salicylic acid, tetrahydrofurfuryl ester;tetrahydrofuran-2-ylmethyl salicylate;SCHEMBL1605649;DTXSID501043224;NSC68484;THURFYL SALICYLATE [WHO-DD];NSC 68484;Tetrahydro-2-furanylmethyl salicylate;AKOS015899692;FT-0754004;A925460;Salicylic acid [(tetrahydrofuran)-2-yl]methyl ester;Q27259924;Benzoic acid, 2-hydroxy-, (tetrahydro-2-furanyl)methyl ester

Chemical Property of Tetrahydrofurfuryl salicylate

Chemical Property:

• Vapor Pressure: 6.71E-05mmHg at 25°C
• Refractive Index: 1.551
• Boiling Point: 334.2 °C at 760 mmHg
• Flash Point: 126.4 °C
• PSA: 55.76000
• Density: 1.224 g/cm³
• LogP: 1.72800
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 222.08920892
• Heavy Atom Count: 16
• Complexity: 241

Purity/Quality:

99%, ^*data from raw suppliers

TetrahydrofurfurylSalicylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(OC1)COC(=O)C2=CC=CC=C2O
• Uses: Tetrahydrofurfuryl Salicylate is a ftetrahydrourfuranyl ester of salicylic ester with potential insecticidal activity.

Technology Process of Tetrahydrofurfuryl salicylate

There total 3 articles about Tetrahydrofurfuryl salicylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Tetrahydrofurfuryl alcohol (97-99-4) + methyl salicylate (119-36-8,8024-54-2) → (tetrahydrofuran-2-yl)methyl 2-hydroxybenzoate (2217-35-8)

Guidance literature:

With N-methyl-N,N,N-trioctylammonium methylcarbonate; In hexane; for 5h; Molecular sieve; Reflux; Green chemistry;

DOI:10.1039/c7gc03858e

Reference yield:

Tetrahydrofurfuryl alcohol (97-99-4) + salicyloyl chloride (1441-87-8) → (tetrahydrofuran-2-yl)methyl 2-hydroxybenzoate (2217-35-8)

Guidance literature:

With benzene;

Reference yield:

→ (tetrahydrofuran-2-yl)methyl 2-hydroxybenzoate (2217-35-8)

Guidance literature:

Salicylsaeure, Tetrahydrofurfurylalkohol;

upstream raw materials:

Tetrahydrofurfuryl alcohol

salicyloyl chloride

methyl salicylate

Refernces