Methanimidamide, N,N-dimethyl-N'-(2-methylphenyl)-

Base Information

• Chemical Name: Methanimidamide, N,N-dimethyl-N'-(2-methylphenyl)-
• CAS No.: 10278-71-4
• Molecular Formula: C10H14 N2
• Molecular Weight: 162.235
• Hs Code.: 2925290090
• European Community (EC) Number: 233-624-9
• NSC Number: 665679
• UNII: U5JVY38RYB
• DSSTox Substance ID: DTXSID4065020
• Nikkaji Number: J69.661G
• ChEMBL ID: CHEMBL1993695
• Mol file: 10278-71-4.mol

Synonyms:Methanimidamide, N,N-dimethyl-N'-(2-methylphenyl)-;10278-71-4;N,N-Dimethyl-N'-o-tolylformamidine;N,N-Dimethyl-N'-(o-tolyl)formamidine;EINECS 233-624-9;NSC665679;U5JVY38RYB;N,N-dimethyl-N'-(2-methylphenyl)methanimidamide;BRN 2802511;N-(o-Tolyl)-N',N'-dimethylformamidine;N1N1-dimethyl-N2-ortho-methylphenylformamidine;FORMAMIDINE, N,N-DIMETHYL-N'-(o-TOLYL)-;(E)-N,N-Dimethyl-N'-(2-methylphenyl)methanimidamide;Methanimidamide, N,N-dimethyl-N'-(2-methylphenyl)-, (E)-;117750-32-0;UNII-U5JVY38RYB;CHEMBL1993695;DTXSID4065020;N,N-Dimethyl-N/'-o-tolylformamidine;AKOS006242083;NSC-665679;LS-69628;NCI60_022666;N,N-Dimethyl-N'-(2-methylphenyl)imidoformamide

Chemical Property of Methanimidamide, N,N-dimethyl-N'-(2-methylphenyl)-

Chemical Property:

• Boiling Point: 251.2oC at 760 mmHg
• Flash Point: 105.7oC
• PSA: 15.60000
• Density: 0.91g/cm3
• LogP: 2.21640
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 162.115698455
• Heavy Atom Count: 12
• Complexity: 152

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N-DIMETHYL-N'-O-TOLYLFORMAMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1N=CN(C)C

Technology Process of Methanimidamide, N,N-dimethyl-N'-(2-methylphenyl)-

There total 6 articles about Methanimidamide, N,N-dimethyl-N'-(2-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

<3-(dimethylamino)-2-azaprop-2-en-1-ylidene> dimethylammonium chloride (20353-93-9) + o-toluidine (95-53-4) → N,N-dimethyl-N'-o-methylphenylformamidine (10278-71-4)

Guidance literature:

DOI:10.1021/jo01310a058

Reference yield: 79.0%

o-toluidine (95-53-4) + N,N-Dimethyl-N'-(dimethylamino-methoxymethyl)-formamidin → N,N-Dimethyl-N'-(o-tolyl)-formamidin (10278-71-4,117750-32-0)

Guidance literature:

at 90 ℃; for 20h;

Reference yield: 67.0%

N-(2-methylphenyl)acetamide (120-66-1) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2-chloro-8-methyl-quinoline-3-carbaldehyde (73568-26-0) + N,N-dimethyl-N'-o-methylphenylformamidine (10278-71-4) + (E)-3-Dimethylamino-2-formyl-N-o-tolyl-acrylamide (78708-01-7)

Guidance literature:

With trichlorophosphate; at 75 ℃; for 15.5h; further temperature;

DOI:10.1039/P19810001520

upstream raw materials:

N,N,N,N,N,N-hexamethylphosphoric triamide

N-(2-methylphenyl)acetamide

N,N-dimethyl-formamide

<3-(dimethylamino)-2-azaprop-2-en-1-ylidene> dimethylammonium chloride

Downstream raw materials:

indole

Refernces

• 1、 Kantlehner, Willi,Hauber, Michael,Haug, Erwin,Schallenmueller, Claus,Regele, Claudia. "Orthoamides. LIV. Contributions to the chemistry of azavinylogous orthoformic acid amide derivatives". . p. 682 - 699. Retrieved 2007/10/03.