3,5-Dibenzyloxybenzyl alcohol

Base Information

• Chemical Name: 3,5-Dibenzyloxybenzyl alcohol
• CAS No.: 24131-31-5
• Molecular Formula: C21H20O3
• Molecular Weight: 320.388
• Hs Code.: 29094990
• Mol file: 24131-31-5.mol

Synonyms:Benzylalcohol, 3,5-bis(benzyloxy)- (8CI);3,5-Bis(benzyloxy)benzenemethanol;3,5-Bis(benzyloxy)benzyl alcohol;[3,5-Bis(benzyloxy)phenyl]methanol;

Chemical Property of 3,5-Dibenzyloxybenzyl alcohol

Chemical Property:

• Appearance/Colour: white to off-white crystals or needles
• Vapor Pressure: 3.21E-11mmHg at 25°C
• Melting Point: 78-81 °C(lit.)
• Refractive Index: 1.614
• Boiling Point: 509.9 °C at 760 mmHg
• PKA: 14.22±0.10(Predicted)
• Flash Point: 262.2 °C
• PSA: 38.69000
• Density: 1.175 g/cm³
• LogP: 4.33690
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dibenzyloxybenzyl Alcohol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3,5-Dibenzyloxybenzyl alcohol

There total 28 articles about 3,5-Dibenzyloxybenzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl 3,5-bis(benzyloxy)benzoate (58605-10-0) → 3,5-dibenzyloxybenzyl alcohol (24131-31-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1055/s-0034-1379988

Reference yield: 99.0%

ethyl 3,5-di(benzyloxy)benzoate (50841-46-8) → 3,5-dibenzyloxybenzyl alcohol (24131-31-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 25 ℃; for 2h; Inert atmosphere;

DOI:10.1002/chem.200802306

Reference yield: 91.0%

5-(hydroxymethyl)benzene-1,3-diol (29654-55-5) + benzyl chloride (100-44-7) → 3,5-dibenzyloxybenzyl alcohol (24131-31-5)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; In acetone; at 70 ℃; for 48h;

DOI:10.1080/00397910801913980

upstream raw materials:

methyl 3,5-bis(benzyloxy)benzoate

3,5-dibenzyloxybenzoic acid

(3,5-di-benzyloxy)benzoic acid benzyl ester

3,5-Dihydroxybenzoic acid

Downstream raw materials:

4-(3',5'-Dibenzyloxy)benzyloxyphthalonitrile

methyl 3,5-bis[[3,5-bis(phenylmethoxy)phenyl]methoxy] benzoate

9-{[3,5-bis(benzyloxy)benzyloxy]methyl}anthracene

2-chloromethyl-4,6-dibenzyloxybenzaldehyde

Refernces

• 1、 Tang, Gang,Hu, Minqi,He, Fuxi,You, Dan,Qian, Yangyang,Bi, Yunmei. "Dendritic poly(benzyl ether)-b-poly(N-vinylcaprolactam) block copolymers: Self-organization in aqueous media, thermoresponsiveness and biocompatibility". . p. 300 - 308. Retrieved 2018.
• 2、 -. "NOVEL FUNCTIONALIZED 1,3-BENZENE DIOLS AND THEIR METHOD OF USE FOR THE TREATMENT OF HEPATIC ENCEPHALOPTHY". . . Retrieved 2016/11/14.