1-allylhydrazine hydrochloride

Base Information

• Chemical Name: 1-allylhydrazine hydrochloride
• CAS No.: 52207-83-7
• Molecular Formula: C3H8 N2 . Cl H
• Molecular Weight: 108.59
• Mol file: 52207-83-7.mol

Synonyms:Allylhydrazine-hydrochloride

Chemical Property of 1-allylhydrazine hydrochloride

Chemical Property:

• Vapor Pressure: 2.71mmHg at 25°C
• Boiling Point: 157.8°Cat760mmHg
• Flash Point: 52.6°C
• PSA: 38.05000
• Density: 0.841g/cm³
• LogP: 1.52890

Purity/Quality:

99% ^*data from raw suppliers

1-Allylhydrazine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-allylhydrazine hydrochloride

There total 2 articles about 1-allylhydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

tert-butyl 2-(prop-2-en-1-yl)hydrazinecarboxylate (192725-90-9) → allylhydrazine dihydrochloride (52207-83-7,70629-62-8,73544-90-8)

Guidance literature:

With hydrogenchloride; In AcOEt; at 0 - 20 ℃; for 1.5h;

Reference yield:

(tert-butoxy)-N-(prop-2-en-1-yl)carbohydrazide (21075-86-5) → allylhydrazine dihydrochloride (52207-83-7,70629-62-8,73544-90-8)

Guidance literature:

With hydrogenchloride; In diethyl ether;

DOI:10.1016/S0040-4039(99)02038-9

Reference yield:

6-(4-cyanophenyl)-2-methoxy-4-methyl-6H-pyrimidine-1,5-dicarboxylic acid 5-methyl ester 1-(4-nitrophenyl) ester (1426800-22-7) + allyl hydrazine hydrochloride (52207-83-7) → 2-allyl-5-(4-cyanophenyl)-7-methyl-3-oxo-2,3,5,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxylic acid methyl ester (1426800-24-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 4h;

upstream raw materials:

(tert-butoxy)-N-(prop-2-en-1-yl)carbohydrazide

tert-butyl 2-(prop-2-en-1-yl)hydrazinecarboxylate

Downstream raw materials:

2-allyl-5-(4-cyanophenyl)-7-methyl-3-oxo-2,3,5,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxylic acid methyl ester

Refernces

• 1、 Brosse, Nicolas,Pinto, Maria-Fatima,Jamart-Grégoire, Brigitte. "N-tert-butoxycarbonylaminophthalimide, a versatile reagent for the conversion of alcohols into alkylated tert-butylcarbazates or hydrazines via the Mitsunobu protocol". . p. 205 - 207. Retrieved 2007/10/03.