Dialuric acid

Base Information

• Chemical Name: Dialuric acid
• CAS No.: 444-15-5
• Molecular Formula: C4H4N2O4
• Molecular Weight: 144.087
• European Community (EC) Number: 207-145-0
• DSSTox Substance ID: DTXSID601265223
• Nikkaji Number: J4.505E
• Wikidata: Q27145999
• Mol file: 444-15-5.mol

Synonyms:dialuric acid;dialuric acid, monohydrate

Chemical Property of Dialuric acid

Chemical Property:

• Refractive Index: 1.551
• Density: 1.696 g/cm³
• XLogP3: -1.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 144.01710661
• Heavy Atom Count: 10
• Complexity: 191

Purity/Quality:

99%, ^*data from raw suppliers

DialuricAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(C(=O)NC(=O)NC1=O)O
• Uses: Dialuric Acid is a metabolite of Alloxan.It is used for testing nutritional vitamin E status. Dialuric acid is a metabolite of Alloxan. Dialuric acid is used for testing nutritional vitamin E status.

Technology Process of Dialuric acid

There total 38 articles about Dialuric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

cis-5,6-dihydroxydihydropyrimidine-2,4-dione (3683-34-9,3952-56-5,20433-38-9,112419-41-7,112419-42-8) → pyrimidine-2,4,5,6(1H,3H)-tetraone (61066-33-9,61066-34-0,61066-35-1,61127-23-9) + 5-hydroxybarbituric acid (444-15-5)

Guidance literature:

With tungestophosphoric acid; sulfuric acid; oxygen; In water; at 25 ℃; for 2.5h; under 750.075 Torr; pH=1; Irradiation;

DOI:10.1055/s-2008-1067086

Reference yield: 58.0%

pyrimidine-2,4,5,6(1H,3H)-tetraone (61066-33-9,61066-34-0,61066-35-1,61127-23-9) → 5-hydroxybarbituric acid (444-15-5)

Guidance literature:

With 2-Amino-4-methylpyridine; In trifluoroacetic acid; for 3h; Ambient temperature;

Reference yield:

pyrimidine-2,4,5,6(1H,3H)-tetraone (61066-33-9,61066-34-0,61066-35-1,61127-23-9) → 5-hydroxybarbituric acid (444-15-5) + oxaluric acid (585-05-7)

Guidance literature:

With hydrogen cyanide; water; potassium carbonate;

upstream raw materials:

6-amino-5-hydroxy-1H-pyrimidine-2,4-dione

pyrimidine-2,4,5,6(1H,3H)-tetraone

L-Cysteine

dihydro-6-hydroxypyrimidine-2,4,5(3H)-trione

Downstream raw materials:

Alloxantin

5-Acetoxy-barbitursaeure

isobutyraldehyde

uric Acid

Refernces

• 1、 TIPSON,CRETCHER. "Reduction of alloxan in aqueous solution. I. By hydrogen sulfide.". . p. 399 - 404. Retrieved 1951.
• 2、 Carraro, Mauro,Sartorel, Andrea,Scorrano, Gianfranco,Carofiglio, Tommaso,Bonchio, Marcella. "Catalytic strategies for sustainable oxidations". experimental part. p. 1971 - 1978. Retrieved 2009/04/07.
• 3、 Schuchmann, Man Nien,Sonntag, Clemens von. "The Radiolysis of Uracil in Oxygenated Aqueous Solutions. A Study by Product Analysis and Pulse Radiolysis". . p. 1525 - 1532. Retrieved 2007/10/02.