Naphtho[2,3-c]furan-1,3-dione

Base Information Edit

Chemical Name:Naphtho[2,3-c]furan-1,3-dione
CAS No.:716-39-2
Molecular Formula:C12H6 O3
Molecular Weight:198.178
Hs Code.:2917399090
European Community (EC) Number:211-936-6
DSSTox Substance ID:DTXSID9061049
Nikkaji Number:J193.086I
Mol file:716-39-2.mol

Synonyms:naphtho[2,3-c]furan-1,3-dione;716-39-2;2,3-Naphthalenedicarboxylic Anhydride;benzo[f][2]benzofuran-1,3-dione;EINECS 211-936-6;Naphtho(2,3-c)furan-1,3-dione;MFCD00059091;naphthalene-2,3-dicarboxylic anhydride;benzo[f]isobenzofuran-1,3-dione;2,3-naphthalic anhydride;SCHEMBL103;DTXSID9061049;AMY11303;2,3-napthalenedicarboxylic anhydride;2,3-napthalene dicarboxylic anhydride;AKOS004907682;FS-4313;1H,3H-naphtho[2,3-c]furan-1,3-dione;SY054023;2,3-naphthalenedicarboxylic acid anhydride;CS-0141898;FT-0609752;N0530;D70358;EN300-218322;A837270;3-[(4,5-DICHLORO-1H-IMIDAZOL-1-YL)METHYL]-N-HYDROXYBENZENECARBOXIMIDAMIDE

Suppliers and Price of Naphtho[2,3-c]furan-1,3-dione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3-NAPHTHALIC ANHYDRIDE
5g
$ 100.00

TRC
2,3-NAPHTHALIC ANHYDRIDE
1g
$ 80.00

TCI Chemical
2,3-Naphthalenedicarboxylic Anhydride >95.0%(GC)(T)
250g
$ 700.00

TCI Chemical
2,3-Naphthalenedicarboxylic Anhydride >95.0%(GC)(T)
25g
$ 175.00

Sigma-Aldrich
2,3-NAPHTHALIC ANHYDRIDE AldrichCPR
1EA
$ 144.00

Sigma-Aldrich
2,3-NAPHTHALIC ANHYDRIDE Aldrich
50mg
$ 144.00

Oakwood
Naphtho[2,3-c]furan-1,3-dione 98%
1g
$ 30.00

Medical Isotopes, Inc.
2,3-NAPHTHALIC ANHYDRIDE
100 mg
$ 605.00

Matrix Scientific
Naphtho[2,3-c]furan-1,3-dione 95+%
10g
$ 158.00

Matrix Scientific
Naphtho[2,3-c]furan-1,3-dione 95+%
5g
$ 101.00

Total 70 raw suppliers

Chemical Property of Naphtho[2,3-c]furan-1,3-dione Edit

Chemical Property:

Vapor Pressure:1.14E-06mmHg at 25°C
Melting Point:246 °C
Boiling Point:401.9°C at 760 mmHg
Flash Point:203.1°C
PSA：43.37000
Density:1.449g/cm³
LogP:2.15040
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:198.031694049
Heavy Atom Count:15
Complexity:280

Purity/Quality:

99%, ^*data from raw suppliers

2,3-NAPHTHALIC ANHYDRIDE ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C2C=C3C(=CC2=C1)C(=O)OC3=O
Description A few years ago, the product was still synthesized from the corresponding diacid, but in recent years, it has been difficult to find the shadow of the diacid in the market, and the sales of this product have been repeatedly restricted, resulting in high prices.
Uses 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.

Technology Process of Naphtho[2,3-c]furan-1,3-dione

There total 15 articles about Naphtho[2,3-c]furan-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%