N~1~,N~2~-Bis[4-(octyloxy)phenyl]ethanediamide

Base Information

• Chemical Name: N~1~,N~2~-Bis[4-(octyloxy)phenyl]ethanediamide
• CAS No.: 19532-76-4
• Molecular Formula: C30H44N2O4
• Molecular Weight: 496.69
• DSSTox Substance ID: DTXSID50560528
• Wikidata: Q82443929
• Mol file: 19532-76-4.mol

Synonyms:N~1~,N~2~-Bis[4-(octyloxy)phenyl]ethanediamide;DTXSID50560528

Chemical Property of N~1~,N~2~-Bis[4-(octyloxy)phenyl]ethanediamide

Chemical Property:

• XLogP3: 9.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 18
• Exact Mass: 496.33010789
• Heavy Atom Count: 36
• Complexity: 519

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCOC1=CC=C(C=C1)NC(=O)C(=O)NC2=CC=C(C=C2)OCCCCCCCC

Technology Process of N~1~,N~2~-Bis[4-(octyloxy)phenyl]ethanediamide

There total 8 articles about N~1~,N~2~-Bis[4-(octyloxy)phenyl]ethanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

4-octyloxyaniline (39905-45-8) + oxalic acid diethyl ester (95-92-1) → N,N'-bis(4-octyloxyphenyl)oxamide (19532-76-4)

Guidance literature:

at 150 ℃; for 17h;

Reference yield: 23.0%

4,4',5,5'-tetrabromo-2,2'-bi-1H-imidazole (98138-00-2) + 4-octyloxyaniline (39905-45-8) → N,N'-bis(4-octyloxyphenyl)oxamide (19532-76-4)

Guidance literature:

at 140 ℃; for 5h;

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → N,N'-bis(4-octyloxyphenyl)oxamide (19532-76-4)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / acetone / 72 h / Heating

2: 83 percent / Sn, 10M HCl / CHCl₃ / 10 h / Heating

3: 23 percent / 5 h / 140 °C

With hydrogenchloride; tin; potassium carbonate; In chloroform; acetone;

upstream raw materials:

1-bromo-octane

N,N'-bis(p-hydroxybenzoyl)hydrazine

N,N'-bis(4-hydroxyphenyl)oxamide

4,4',5,5'-tetrabromo-2,2'-bi-1H-imidazole

Refernces

• 1、 Crossley, Maxwell J.,Gorjian, Sargon,Sternhell, Sever,Tansey, Kerrie M.. "The Synthesis of Some Lipophilic Tetradentate Ligands for Use in the Formation of Metal-Linked Polymers". . p. 723 - 738. Retrieved 2007/10/02.
• 2、 -. "Piperidine derivatives". . . Retrieved 2008/06/13.