2-Propanone, 1,3-diphenyl-, O-acetyloxime

Base Information

• Chemical Name: 2-Propanone, 1,3-diphenyl-, O-acetyloxime
• CAS No.: 19689-93-1
• Molecular Formula: C17H17NO2
• Molecular Weight: 267.327
• Mol file: 19689-93-1.mol

Synonyms:

Chemical Property of 2-Propanone, 1,3-diphenyl-, O-acetyloxime

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propanone, 1,3-diphenyl-, O-acetyloxime

There total 3 articles about 2-Propanone, 1,3-diphenyl-, O-acetyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

1,3-diphenylpropan-2-one oxime (1788-31-4) + acetyl chloride (75-36-5) → 1,3-Diphenylpropanone oxime O-acetate (19689-93-1) + Acetic acid (E)-2-diacetylamino-1,3-diphenyl-allyl ester

Guidance literature:

With pyridine; acetic anhydride; Heating;

Reference yield:

1,3-diphenylpropan-2-one oxime (1788-31-4) + acetyl chloride (75-36-5) → 1,3-Diphenylpropanone oxime O-acetate (19689-93-1)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1002/anie.202110901

Reference yield:

1,3-Diphenylpropanone (102-04-5) → 1,3-Diphenylpropanone oxime O-acetate (19689-93-1)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / methanol / 20 °C / Inert atmosphere

2: triethylamine / dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere

With hydroxylamine hydrochloride; sodium acetate; triethylamine; In methanol; dichloromethane;

DOI:10.1002/anie.202110901

upstream raw materials:

1,3-diphenylpropan-2-one oxime

acetyl chloride

1,3-Diphenylpropanone

Downstream raw materials:

1,3-dibenzylisoquinoline

2-benzyl-6-methyl-3-phenylpyridine

1,3-Diphenylpropanone

Refernces

• 1、 Reddy, Gaddam Subba,Bhatt, M. Vivekananda. "A New Reaction of Oximes - Formation of Isomeric α- and α'-Acyloxyenimides". . p. 213 - 215. Retrieved 2007/10/02.