1-(5-BROMO-4-NITRO-2-THIENYL)ETHAN-1-ONE

Base Information

• Chemical Name: 1-(5-BROMO-4-NITRO-2-THIENYL)ETHAN-1-ONE
• CAS No.: 2160-55-6
• Molecular Formula: C6H4BrNO3S
• Molecular Weight: 250.073
• Hs Code.: 2934999090
• Mol file: 2160-55-6.mol

Synonyms:1-(5-Bromo-4-nitro-2-thienyl)ethan-1-one;1-(5-bromo-4-nitro-[2]thienyl)-ethanone;1-(5-bromo-4-nitro-thiophen-2-yl)-ethanone;2-Brom-3-nitro-5-acetyl-thiophen;5-Acetyl-2-brom-3-nitrothiophen;2-bromo-3-nitro-5-acetyl thiophene;1-(5-Brom-4-nitro-[2]thienyl)-aethanon;2-Acetyl-5-bromo-4-nitrothiophene;

Chemical Property of 1-(5-BROMO-4-NITRO-2-THIENYL)ETHAN-1-ONE

Chemical Property:

• Vapor Pressure: 0.000997mmHg at 25°C
• Melting Point: 103-103.5 °C
• Boiling Point: 302.3oC at 760 mmHg
• Flash Point: 136.6oC
• PSA: 91.13000
• Density: 1.805g/cm3
• LogP: 3.14460

Purity/Quality:

97% ^*data from raw suppliers

2-Acetyl-5-bromo-4-nitrothiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(5-BROMO-4-NITRO-2-THIENYL)ETHAN-1-ONE

There total 1 articles about 1-(5-BROMO-4-NITRO-2-THIENYL)ETHAN-1-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Acetyl-5-bromothiophene (5370-25-2) → 1-(5-bromo-4-nitro-thiophen-2-yl)-ethanone (2160-55-6)

Guidance literature:

With sulfuric acid; nitric acid; at -10 - -5 ℃;

Reference yield:

1-(5-bromo-4-nitro-thiophen-2-yl)-ethanone (2160-55-6) + aniline (62-53-3) → 5-acetyl-2-phenylamino-3-nitrothiophene (1087-13-4) + aniline hydrobromide (542-11-0)

Guidance literature:

In methanol; at 20 ℃; Rate constant; Thermodynamic data; ΔH(excit.), ΔS(excit.);

DOI:10.1039/P29940002187

Reference yield:

1-(5-bromo-4-nitro-thiophen-2-yl)-ethanone (2160-55-6) → 2-Amino-5-acetyl-3-nitrothiophen (1009-57-0)

Guidance literature:

With hexamethylenetetramine; In water;

upstream raw materials:

2-Acetyl-5-bromothiophene

Downstream raw materials:

1-(4-Nitro-5-p-tolylamino-thiophen-2-yl)-ethanone

1-[5-(4-methoxy-anilino)-4-nitro-thiophen-2-yl]-ethanone

1-(5-phenylsulfanyl-4-nitro-2-thienyl)ethanone

5-acetyl-2-phenylamino-3-nitrothiophene