Technology Process of Benzenenonanoic acid methyl ester
There total 14 articles about Benzenenonanoic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol;
at 20 ℃;
for 2h;
atmospheric pressure;
DOI:10.1021/ac051141s
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 100 percent / oxalyl chloride; DMSO / CH2Cl2 / 0.25 h / -55 °C
2.1: NaH / tetrahydrofuran / 0.5 h / 0 °C
2.2: 86 percent / tetrahydrofuran / 0.25 h / 0 °C
3.1: 91 percent / H2 / Pd/C / methanol / 7500.6 Torr
4.1: 77 percent / DIBALH / CH2Cl2 / 0.5 h / -75 °C
5.1: NaH / tetrahydrofuran / 0.5 h / 0 °C
5.2: 79.3 percent / tetrahydrofuran / 0.25 h / 0 °C
6.1: 91 percent / H2 / Pd/C / methanol / 7500.6 Torr
With
oxalyl dichloride; hydrogen; sodium hydride; diisobutylaluminium hydride; dimethyl sulfoxide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane;
1.1: Oxidation / 2.1: deprotonation / 2.2: Condensation / 3.1: Hydrogenation / 4.1: Reduction / 5.1: deprotonation / 5.2: Condensation / 6.1: Hydrogenation;
DOI:10.1016/S0968-0896(99)00253-9
