Peimine

Base Information

• Chemical Name: Peimine
• CAS No.: 23496-41-5
• Molecular Formula: C₂₇H₄₅NO₃
• Molecular Weight: 431.659
• Hs Code.: 29420000
• European Community (EC) Number: 683-168-3
• UNII: 34QDF8UFSY
• DSSTox Substance ID: DTXSID70910283
• Mol file: 23496-41-5.mol

Synonyms:5a-Cevane-3b,6a,20-triol (8CI);Verticine (6CI,7CI);Dihydroisoimperialine;Peimine;Verticine;

Chemical Property of Peimine

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 2.74E-15mmHg at 25°C
• Melting Point: 233-234oC
• Refractive Index: 1.591
• Boiling Point: 568.4 °C at 760 mmHg
• PKA: 9.5(at 25℃)
• Flash Point: 275.3 °C
• PSA: 63.93000
• Density: 1.18 g/cm³
• LogP: 3.61600
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: Acetonitrile (Slightly, Heated, Sonicated), Chloroform (Slightly), Ethanol (Slig
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 431.33994430
• Heavy Atom Count: 31
• Complexity: 715

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

Peimine ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O
• Isomeric SMILES: C[C@H]1CC[C@H]2[C@@]([C@H]3CC[C@@H]4[C@H]([C@@H]3CN2C1)C[C@H]5[C@H]4C[C@@H]([C@@H]6[C@@]5(CC[C@@H](C6)O)C)O)(C)O
• Description: Fritillaria verticillata var. Thunbergii also yields this steroidal alkaloid which was originally given the formulae ClsH3302N or C19H3S02N. The base has [α]10D -10.66° (EtOH), yields a crystalline perchlorate, a platinichloride, and contains three non-phenolic hydroxyl groups. The nitrogen atom is tertiary in character. Chi and his colleagues regard the alkaloid as identical with Peimine (q.v.).
• Uses: Peimine is a steroidal alkaloid compound extracted from the Fritillaria species of medicinal plants.

Technology Process of Peimine

There total 6 articles about Peimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

C29H47NO4 → isobaimonidine (74184-79-5) + verticine (23496-41-5)

Guidance literature:

Reference yield:

→ verticine (23496-41-5)

Guidance literature:

With ethanol; sodium;

DOI:10.1021/ja01198a008

Reference yield:

C27H45NO4 (77410-34-5) → verticine (23496-41-5)

Guidance literature:

With acetic acid; triphenylphosphine;

upstream raw materials:

C₂₇H₄₅NO₄

C₂₉H₄₅NO₄

Downstream raw materials:

korselidinedione

C₂₇H₄₃NO₃

Refernces

• 1、 Kitajima, Junichi,Noda, Naoki,Ida, Yoshiteru,Miyahara, Kazumoto,Kwasaki, Toshio. "STEROID ALKALOIDS OF FRESH BULBS OF FRITILLARIA THUNBERGII MIQ. AND OF CRUDE DRUG "BAI-MO" PREPARED THEREFROM". . p. 791 - 796. Retrieved 2007/10/02.