1,2-BIS(1H-BENZIMIDAZOL-2-YL)ETHANE-1,2-DIOL

Base Information

• Chemical Name: 1,2-BIS(1H-BENZIMIDAZOL-2-YL)ETHANE-1,2-DIOL
• CAS No.: 3314-32-7
• Molecular Formula: C16H14 N4 O2
• Molecular Weight: 294.313
• Hs Code.: 2933990090
• Mol file: 3314-32-7.mol

Synonyms:1,2-Ethanediol,1,2-bis(2-benzimidazolyl)- (6CI,7CI,8CI);1,2-Bis(2-benzimidazolyl)-1,2-dihydroxyethane; 1,2-Bis(2-benzimidazolyl)-1,2-ethanediol;NSC 127160; NSC 70380

Chemical Property of 1,2-BIS(1H-BENZIMIDAZOL-2-YL)ETHANE-1,2-DIOL

Chemical Property:

• Vapor Pressure: 3.65E-22mmHg at 25°C
• Boiling Point: 726.7°Cat760mmHg
• Flash Point: 393.3°C
• PSA: 97.82000
• Density: 1.542g/cm³
• LogP: 2.20620

Purity/Quality:

98%min ^*data from raw suppliers

1,2-Bis(1H-benzimidazol-2-yl)ethane-1,2-diol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-BIS(1H-BENZIMIDAZOL-2-YL)ETHANE-1,2-DIOL

There total 5 articles about 1,2-BIS(1H-BENZIMIDAZOL-2-YL)ETHANE-1,2-DIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

→ 1,2-bis(1H-benzo[d]imidazol-2-yl)ethane-1,2-diol (3314-32-7)

Guidance literature:

Reference yield: 66.2%

tartaric acid (87-69-4,138508-61-9) + 1,2-diamino-benzene (95-54-5) → 1,2-bis(1H-benzo[d]imidazol-2-yl)ethane-1,2-diol (3314-32-7)

Guidance literature:

With hydrogenchloride; In water; at 120 ℃; for 12h;

DOI:10.1016/j.jorganchem.2015.01.033

Reference yield: 65.0%

L-Tartaric acid (87-69-4,138508-61-9) + 1,2-diamino-benzene (95-54-5) → Δ-1,2-bis-(1H-benzimidazol-2-yl)-1,2-ethanediol (3314-32-7,37526-16-2)

Guidance literature:

DOI:10.1016/j.jorganchem.2011.08.007

upstream raw materials:

L-Tartaric acid

1,2-diamino-benzene

D-tartaric acid

tartaric acid

Downstream raw materials:

SnPh₂Cl(1,2-bis(1H-benzimidazol-2-yl)ethane-1,2-diol(-1H))

Refernces

• 1、 Parveen, Shazia,Arjmand, Farukh. "De novo design, synthesis and spectroscopic characterization of chiral benzimidazole-derived amino acid Zn(II) complexes: Development of tryptophan-derived specific hydrolytic DNA artificial nuclease agent". . p. 53 - 60. Retrieved 2012.
• 2、 Arjmand, Farukh,Parveen, Shazia,Afzal, Mohd.,Shahid, Mohd.. "Synthesis, characterization, biological studies (DNA binding, cleavage, antibacterial and topoisomerase I) and molecular docking of copper(II) benzimidazole complexes". . p. 15 - 26. Retrieved 2012.
• 3、 Rosenfeld et al.. "-". . p. 5907. Retrieved 1951.