2-Nitroacridine

Base Information

• Chemical Name: 2-Nitroacridine
• CAS No.: 29808-81-9
• Molecular Formula: C13H8N2O2
• Molecular Weight: 224.219
• Hs Code.: 2933990090
• NSC Number: 170669
• DSSTox Substance ID: DTXSID60305402
• Nikkaji Number: J596.911E
• Wikidata: Q82052027
• ChEMBL ID: CHEMBL2005055
• Mol file: 29808-81-9.mol

Synonyms:2-Nitroacridine;29808-81-9;7-nitroacridine;NSC170669;POTASSIUMACRYLATE;CHEMBL2005055;DTXSID60305402;NSC-170669;AS-56603;CS-0359347;D93049

Chemical Property of 2-Nitroacridine

Chemical Property:

• Vapor Pressure: 2.27E-07mmHg at 25°C
• Melting Point: 210-212 °C
• Refractive Index: 1.754
• Boiling Point: 435.2 °C at 760 mmHg
• PKA: 3.59±0.10(Predicted)
• Flash Point: 217 °C
• PSA: 58.71000
• Density: 1.377 g/cm³
• LogP: 3.81940
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 224.058577502
• Heavy Atom Count: 17
• Complexity: 302

Purity/Quality:

98.5% ^*data from raw suppliers

2-NITROACRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=C3C=C(C=CC3=N2)[N+](=O)[O-]

Technology Process of 2-Nitroacridine

There total 12 articles about 2-Nitroacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

acridine (260-94-6) → 2-Nitroacridine (29808-81-9)

Guidance literature:

With sulfuric acid; nitric acid; at 0 - 2 ℃; for 3h;

Reference yield:

acridine (260-94-6) → 4-Nitroacridine (42955-73-7) + 1-Nitroacridine (30904-48-4) + 2-Nitroacridine (29808-81-9) + 10H-acridin-9-one (578-95-0,790240-54-9)

Guidance literature:

With water; Nitrate; Kinetics; Irradiation;

DOI:10.1016/S0045-6535(98)00188-X

Reference yield:

o-aminobenzaldehyde (529-23-7) + para-nitrophenyl bromide (586-78-7) → 2-Nitroacridine (29808-81-9)

Guidance literature:

With copper; sodium carbonate; nitrobenzene; at 220 ℃; und Behandeln des Reaktionsprodukts mit konz.Schwefelsaeure;

upstream raw materials:

acridine

7-nitro-9-chloroacridine

o-aminobenzaldehyde

para-nitrophenyl bromide

Downstream raw materials:

2-aminoacridine

2-nitroacridone

Refernces

• 1、 Beitz, Toralf,Bechmann, Wolfgang,Mitzner, Rolf. "Investigation on the photoreactions of nitrate and nitrite ions with selected azaarenes in water". . p. 351 - 361. Retrieved 2007/10/03.