Go-6976

Base Information

• Chemical Name: Go-6976
• CAS No.: 136194-77-9
• Molecular Formula: C₂₄H₁₈N₄O
• Molecular Weight: 378.433
• Hs Code.: 2933998090
• UNII: B9IQO7JZ16
• DSSTox Substance ID: DTXSID70159731
• Nikkaji Number: J636.731C
• Wikipedia: Go_6976
• Wikidata: Q27077832
• Pharos Ligand ID: MFR2SAR9FGQX
• Metabolomics Workbench ID: 57965
• ChEMBL ID: CHEMBL302449
• Mol file: 136194-77-9.mol

Synonyms:Go 6976;Go-6976;Go6976;Goe 6976

Chemical Property of Go-6976

Chemical Property:

• Appearance/Colour: Off-white to yellow solid
• Vapor Pressure: 6.76E-17mmHg at 25°C
• Refractive Index: 1.773
• Boiling Point: 652.3 °C at 760 mmHg
• PKA: 14.39±0.20(Predicted)
• Flash Point: 348.3 °C
• PSA: 62.75000
• Density: 1.41 g/cm³
• LogP: 4.92528
• Storage Temp.: −20°C
• Solubility.: Acetonitrile (Very Slightly, Heated), DMSO (Slightly), Methanol (Very Slightly,
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 378.14806121
• Heavy Atom Count: 29
• Complexity: 730

Purity/Quality:

98% min ^*data from raw suppliers

Go 6976 ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN1C2=CC=CC=C2C3=C4C(=C5C6=CC=CC=C6N(C5=C31)CCC#N)CNC4=O
• Uses: Go 6976 is a potent FLT3 inihibtor which is been shown to initiate cytotoxicity involving acute leukemia. Also known as a PKC inhibitor, which results into apoptosis and tumor destruction. Cancer therapeutic agent.

Technology Process of Go-6976

There total 1 articles about Go-6976 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl iodide (74-88-4) + NGIC-I → Go 6976 (136194-77-9)

Guidance literature:

In N-methyl-acetamide; mineral oil;

upstream raw materials:

methyl iodide

Refernces