1-(Naphthalen-1-yl)ethanaMine HCl

Base Information

• Chemical Name: 1-(Naphthalen-1-yl)ethanaMine HCl
• CAS No.: 40280-57-7
• Molecular Formula: C12H13N.ClH
• Molecular Weight: 207.69900
• Hs Code.: 2921499090
• Mol file: 40280-57-7.mol

Synonyms:4-Morpholineacetic acid,2,6-xylyl ester,hydrochloride;FC 421;2,6-Xylyl ester of 4-morpholineacetic acid hydrochloride;naphthylethylammonium chloride;Hydrochlorid v. Morpholino-essigsaeure-<2,6-dimethyl-phenylester>;

Chemical Property of 1-(Naphthalen-1-yl)ethanaMine HCl

Chemical Property:

• PSA: 26.02000
• LogP: 4.36180
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

1-Methyl-1-naphthalen-1-yl-ethylaminehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(Naphthalen-1-yl)ethanaMine HCl

There total 8 articles about 1-(Naphthalen-1-yl)ethanaMine HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-ethylnapthelene (1127-76-0) → hydrochloride of <1-(1-naphthyl)ethyl>amine (40280-57-7)

Guidance literature:

1-ethylnapthelene; With Benzophenone imine; iodobenzene dimethoxide; at 75 ℃; for 24h; Inert atmosphere; Irradiation;

With hydrogenchloride; In methanol; water; at 45 ℃; for 24h; Inert atmosphere; Irradiation;

DOI:10.1002/chem.202102627

Reference yield: 72.0%

N-(1-naphthalen-1-yl-ethyl)-P,P-diphenylphosphinamide (344248-49-3) → hydrochloride of <1-(1-naphthyl)ethyl>amine (40280-57-7)

Guidance literature:

With hydrogenchloride; In benzene;

DOI:10.1055/s-1982-29774

Reference yield:

acetonaphthoneimine → hydrochloride of <1-(1-naphthyl)ethyl>amine (40280-57-7)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 2h; Yield given; Ambient temperature;

DOI:10.1002/ardp.19933260607

upstream raw materials:

N-(1-naphthalen-1-yl-ethyl)-P,P-diphenylphosphinamide

1-(1-naphthyl)ethanol

1-Cyanonaphthalene

1-(1-naphthalenyl)ethanone oxime

Downstream raw materials:

N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Refernces

• 1、 Kramer, S?ren. "Synthesis of α-Substituted Primary Benzylamines through Copper-Catalyzed Cross-Dehydrogenative Coupling". supporting information. p. 65 - 69. Retrieved 2019/01/04.
• 2、 Krzyzanowska, B.,Stec, W. J.. "A Study of the Synthesis of Optically Active Amines from Prochiral N-Phosphinylimines". . p. 270 - 273. Retrieved 2007/10/02.