Curzerene

Base Information

• Chemical Name: Curzerene
• CAS No.: 17910-09-7
• Molecular Formula: C₁₅H₂₀O
• Molecular Weight: 216.323
• Mol file: 17910-09-7.mol

Synonyms:Curzerene;

Chemical Property of Curzerene

Chemical Property:

• Boiling Point: 282.8±40.0℃ (760 Torr)
• Flash Point: 117.5±14.2℃
• PSA: 13.14000
• Density: 0.982±0.06 g/cm3 (20 ºC 760 Torr)
• LogP: 4.07120

Purity/Quality:

≥98% ^*data from raw suppliers

Curzerene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Curzerene

There total 1 articles about Curzerene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(5S,6S)-5-Isopropenyl-3,6-dimethyl-6-vinyl-5,6,7,7a-tetrahydro-4H-benzofuran-2-one (20267-89-4,121468-65-3) → isofuranogermacrene (17910-09-7,115589-78-1,120520-43-6,121470-80-2)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; toluene; at -30 - -10 ℃; for 4h;

DOI:10.1016/S0040-4020(01)85916-0

Reference yield: 8.0%

isofuranogermacrene (17910-09-7,115589-78-1,120520-43-6,121470-80-2) → 8β-hydroxy-isogermafurenolide (20267-91-8,121470-81-3) + 8β-hydroperoxy-isogermafurenolide (121429-35-4)

Guidance literature:

With platinum(IV) oxide; oxygen; In benzene; for 10h; under 735.5 Torr; Ambient temperature;

DOI:10.1016/S0040-4020(01)85916-0

Reference yield:

isofuranogermacrene (17910-09-7,115589-78-1,120520-43-6,121470-80-2) → 8β-hydroxy-isogermafurenolide (20267-91-8,121470-81-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 8 percent / O₂, PtO₂ / benzene / 10 h / 735.5 Torr / Ambient temperature

2: triphenylphosphine / CDCl₃

With platinum(IV) oxide; oxygen; triphenylphosphine; In chloroform-d1; benzene;

DOI:10.1016/S0040-4020(01)85916-0

upstream raw materials:

(5S,6S)-5-Isopropenyl-3,6-dimethyl-6-vinyl-5,6,7,7a-tetrahydro-4H-benzofuran-2-one

Downstream raw materials:

8β-hydroxy-isogermafurenolide

8β-hydroperoxy-isogermafurenolide

Refernces