17alpha-Hydroxy-4-pregnen-3-one

Base Information

• Chemical Name: 17alpha-Hydroxy-4-pregnen-3-one
• CAS No.: 3090-78-6
• Molecular Formula: C₂₁H₃₂O₂
• Molecular Weight: 316.484
• Mol file: 3090-78-6.mol

Synonyms:17a-Hydroxy-4-pregnen-3-one

Chemical Property of 17alpha-Hydroxy-4-pregnen-3-one

Chemical Property:

• Vapor Pressure: 7.01E-10mmHg at 25°C
• Boiling Point: 447.3°Cat760mmHg
• Flash Point: 190.6°C
• PSA: 37.30000
• Density: 1.09g/cm³
• LogP: 4.65940

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 17alpha-Hydroxy-4-pregnen-3-one

There total 6 articles about 17alpha-Hydroxy-4-pregnen-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.7%

ethisterone (434-03-7,17554-63-1,41460-94-0,83509-38-0,95118-48-2,95975-56-7) → 17α-Aethyl-testosteron (1235-97-8,2826-11-1,3090-78-6,4220-86-4) + 17-Vinyl-testosteron (1235-98-9,4244-02-4)

Guidance literature:

With 1-hexene; hydrogen; palladium, 5% on calcium carbonate, poisoned with lead; In methanol; at 40 - 60 ℃; for 5.5h; under 1292.9 Torr;

Reference yield:

→ 17α-Ethyl-9β,10α-testosteron (1235-97-8,2826-11-1,3090-78-6,4220-86-4)

Guidance literature:

Acetat, LiAlH4;

Reference yield:

→ (10S,13S,17S)-17-Ethyl-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one (1235-97-8,2826-11-1,3090-78-6,4220-86-4)

Guidance literature:

upstream raw materials:

ethisterone

17,20β_F-epoxy-pregn-4-en-3-one

Refernces