3-Butenoic acid, 2-methyl-, methyl ester

Base Information

• Chemical Name: 3-Butenoic acid, 2-methyl-, methyl ester
• CAS No.: 51747-33-2
• Molecular Formula: C6H10O2
• Molecular Weight: 114.144
• Mol file: 51747-33-2.mol

Synonyms:Methyl 2-methyl-3-butenoate;3-Butenoic acid,2-methyl-,methyl ester;

Chemical Property of 3-Butenoic acid, 2-methyl-, methyl ester

Chemical Property:

• PSA: 26.30000
• LogP: 0.98150

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Butenoic acid, 2-methyl-, methyl ester

There total 6 articles about 3-Butenoic acid, 2-methyl-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.6%

π-crotyl palladium chloride (35037-11-7) + Methyl formate (107-31-3) → methyl (E)-pent-3-enoate (818-58-6) + methyl 2-methyl-3-butenoate (51747-33-2) + cis-3-pentenoic acid methyl ester (36781-66-5) + palladium (7440-05-3)

Guidance literature:

With carbon monoxide; sodium butyrate; In neat (no solvent); mixt. of PdCl(C3H5), HCO2Me, Na butyrate (as nucleophile) stirred at room temp. for 30 min, addn. of CO, react. time 2 h; react. mixt. filtered, colourless liquid analysed by GLC;

DOI:10.1016/0304-5102(89)80136-1

Reference yield: 62.0%

3-methyl-3-methoxycarbonyl-4,5-dihydro-1H-pyrazole (6117-22-2) → methyl angelate (5953-76-4) + methyl (E)-2-methyl-2-butenoate (6622-76-0) + methyl 2-methyl-3-butenoate (51747-33-2) + methyl 1-methylcyclopropanecarboxylate (6206-25-3)

Guidance literature:

at 155 ℃; for 20h;

DOI:10.1021/jo00142a013

Reference yield: 41.3%

methanol (67-56-1) + π-crotyl palladium chloride (35037-11-7) → methyl (E)-pent-3-enoate (818-58-6) + methyl 2-methyl-3-butenoate (51747-33-2) + cis-3-pentenoic acid methyl ester (36781-66-5) + palladium (7440-05-3)

Guidance literature:

With carbon monoxide; sodium butyrate; In neat (no solvent); mixt. of PdCl(C3H5), MeOH, Na butyrate (as nucleophile) stirred at room temp. for 30 min, addn. of CO, react. time 2 h; react. mixt. filtered, colourless liquid analysed by GLC;

DOI:10.1016/0304-5102(89)80136-1

upstream raw materials:

methanol

crotylamine

carbon monoxide

3-methyl-3-methoxycarbonyl-4,5-dihydro-1H-pyrazole

Downstream raw materials:

ethyl 2-<<(p-nitrophenyl)sulfonyl>oxy>-3-phenyl-3-butenoate

methyl 2-methyl-4-<<(p-nitrophenyl)sulfonyl>oxy>-2-butenoate

ethyl 2-(N-methyl-N-benzylamino)-3-phenyl-3-butenoate

methyl 2-methyl-4-(N-methyl-N-benzylamino)-2-butenoate

Refernces

• 1、 Mori, Sadayuki,Matsuyoshi, Hiroaki,Kudo, Kiyoshi,Sugita, Nobuyuki. "Cobalt-Catalyzed Photochemical Carbonylation of Allylic Amines". . p. 1397 - 1400. Retrieved 2007/10/02.
• 2、 Doyle, Michael P.,Dorow, Roberta L.,Tamblyn, William H.. "Cyclopropanation of α,β-Unsaturated Carbonyl Compounds and Nitriles with Diazo Compounds. The nature of the Involvement of Transition-Metal Promoters". . p. 4059 - 4068. Retrieved 2007/10/02.